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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC16A6
All Species:
8.79
Human Site:
S141
Identified Species:
21.48
UniProt:
O15403
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15403
NP_004685.2
523
57393
S141
L
P
T
V
T
I
L
S
Q
Y
F
G
K
R
R
Chimpanzee
Pan troglodytes
XP_523697
523
57341
S141
L
P
T
V
T
I
L
S
Q
Y
F
G
K
R
R
Rhesus Macaque
Macaca mulatta
XP_001116628
478
52163
K142
I
G
K
Y
F
Y
R
K
R
P
M
A
N
G
L
Dog
Lupus familis
XP_548022
523
57111
S141
L
P
T
V
T
I
L
S
Q
Y
F
D
K
R
R
Cat
Felis silvestris
Mouse
Mus musculus
P57787
470
50355
N142
I
M
L
N
R
Y
F
N
K
R
R
P
I
A
N
Rat
Rattus norvegicus
O35910
471
50530
N142
I
M
L
N
R
Y
F
N
K
R
R
P
M
A
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507090
482
52573
N142
I
G
K
Y
F
Y
K
N
R
P
I
A
N
G
L
Chicken
Gallus gallus
Q90632
542
58161
G140
Q
P
S
L
I
M
L
G
T
Y
F
D
K
R
R
Frog
Xenopus laevis
Q6GM59
460
50319
R141
V
G
K
Y
F
E
K
R
K
A
L
A
Y
G
I
Zebra Danio
Brachydanio rerio
Q503M4
477
51835
R141
V
G
I
Y
F
C
E
R
K
A
L
A
Y
G
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
31.5
86
N.A.
29.4
25.2
N.A.
30
23.6
30
27.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
48.1
93.1
N.A.
46.6
41.6
N.A.
47.9
42.2
48.9
47
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
93.3
N.A.
0
0
N.A.
0
46.6
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
93.3
N.A.
20
20
N.A.
20
66.6
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
20
0
40
0
20
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% D
% Glu:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
40
0
20
0
0
0
40
0
0
0
0
% F
% Gly:
0
40
0
0
0
0
0
10
0
0
0
20
0
40
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
40
0
10
0
10
30
0
0
0
0
10
0
10
0
20
% I
% Lys:
0
0
30
0
0
0
20
10
40
0
0
0
40
0
0
% K
% Leu:
30
0
20
10
0
0
40
0
0
0
20
0
0
0
20
% L
% Met:
0
20
0
0
0
10
0
0
0
0
10
0
10
0
0
% M
% Asn:
0
0
0
20
0
0
0
30
0
0
0
0
20
0
20
% N
% Pro:
0
40
0
0
0
0
0
0
0
20
0
20
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
30
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
20
0
10
20
20
20
20
0
0
40
40
% R
% Ser:
0
0
10
0
0
0
0
30
0
0
0
0
0
0
0
% S
% Thr:
0
0
30
0
30
0
0
0
10
0
0
0
0
0
0
% T
% Val:
20
0
0
30
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
40
0
40
0
0
0
40
0
0
20
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _