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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC16A3
All Species:
29.39
Human Site:
S221
Identified Species:
64.67
UniProt:
O15427
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15427
NP_001035887.1
465
49469
S221
S
R
R
L
L
D
L
S
V
F
R
D
R
G
F
Chimpanzee
Pan troglodytes
XP_511760
480
51139
S238
S
R
R
L
L
D
L
S
V
F
R
D
R
G
F
Rhesus Macaque
Macaca mulatta
XP_001113138
465
49454
S221
S
R
R
L
L
D
L
S
V
F
R
D
R
G
F
Dog
Lupus familis
XP_540498
470
50429
S222
S
R
R
L
L
D
L
S
V
F
R
D
R
G
F
Cat
Felis silvestris
Mouse
Mus musculus
P57787
470
50355
S225
P
Q
R
L
L
D
L
S
V
F
R
D
R
G
F
Rat
Rattus norvegicus
O35910
471
50530
S225
S
P
R
L
L
D
L
S
V
F
R
D
R
G
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519725
787
84186
S187
R
K
K
L
L
D
F
S
I
F
T
E
R
G
F
Chicken
Gallus gallus
P57788
473
51023
S225
K
K
K
L
L
D
F
S
V
F
K
D
G
G
F
Frog
Xenopus laevis
Q6GM59
460
50319
H239
Y
C
T
T
K
E
Y
H
F
L
L
K
P
K
F
Zebra Danio
Brachydanio rerio
Q503M4
477
51835
H246
F
Q
S
M
Q
E
Y
H
F
L
L
M
P
D
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P36032
473
52324
A249
Y
D
V
L
S
N
F
A
V
W
L
L
F
G
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.4
97.8
88.3
N.A.
88.7
88.7
N.A.
37.8
78
35
35.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
95.8
99.1
92.9
N.A.
92.7
92.7
N.A.
45.6
84.5
52.6
54.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
86.6
93.3
N.A.
53.3
60
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
80
80
13.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
73
0
0
0
0
0
64
0
10
0
% D
% Glu:
0
0
0
0
0
19
0
0
0
0
0
10
0
0
0
% E
% Phe:
10
0
0
0
0
0
28
0
19
73
0
0
10
0
100
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
10
82
0
% G
% His:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
10
19
19
0
10
0
0
0
0
0
10
10
0
10
0
% K
% Leu:
0
0
0
82
73
0
55
0
0
19
28
10
0
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
10
0
0
0
0
0
0
0
0
0
0
19
0
0
% P
% Gln:
0
19
0
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
37
55
0
0
0
0
0
0
0
55
0
64
0
0
% R
% Ser:
46
0
10
0
10
0
0
73
0
0
0
0
0
0
0
% S
% Thr:
0
0
10
10
0
0
0
0
0
0
10
0
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
73
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
19
0
0
0
0
0
19
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _