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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC16A3 All Species: 33.64
Human Site: S58 Identified Species: 74
UniProt: O15427 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15427 NP_001035887.1 465 49469 S58 Q E F G I G Y S D T A W I S S
Chimpanzee Pan troglodytes XP_511760 480 51139 S75 Q E F G I G Y S D T A W I S S
Rhesus Macaque Macaca mulatta XP_001113138 465 49454 S58 R E F G I G Y S D T A W I S S
Dog Lupus familis XP_540498 470 50429 S58 R E F G I G Y S D T A W I S S
Cat Felis silvestris
Mouse Mus musculus P57787 470 50355 S58 H E F G I G Y S D T A W I S S
Rat Rattus norvegicus O35910 471 50530 S58 H E F G I G Y S D T A W I S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519725 787 84186 S356 R D F G V G Y S D T A W I S S
Chicken Gallus gallus P57788 473 51023 S58 R E F G V G Y S D T A W I S S
Frog Xenopus laevis Q6GM59 460 50319 A55 S Y F A Q D Y A R T A W I H S
Zebra Danio Brachydanio rerio Q503M4 477 51835 S55 M H F A K D Y S G T A W I H S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36032 473 52324 G77 L E N N T F A G G S K L D Y A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.4 97.8 88.3 N.A. 88.7 88.7 N.A. 37.8 78 35 35.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 95.8 99.1 92.9 N.A. 92.7 92.7 N.A. 45.6 84.5 52.6 54.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 93.3 N.A. 93.3 93.3 N.A. 80 86.6 46.6 53.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 100 100 53.3 53.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 41 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 19 0 0 10 10 0 0 91 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 19 0 0 73 0 0 0 10 0 0 % D
% Glu: 0 73 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 91 0 0 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 73 0 73 0 10 19 0 0 0 0 0 0 % G
% His: 19 10 0 0 0 0 0 0 0 0 0 0 0 19 0 % H
% Ile: 0 0 0 0 55 0 0 0 0 0 0 0 91 0 0 % I
% Lys: 0 0 0 0 10 0 0 0 0 0 10 0 0 0 0 % K
% Leu: 10 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 19 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 37 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % R
% Ser: 10 0 0 0 0 0 0 82 0 10 0 0 0 73 91 % S
% Thr: 0 0 0 0 10 0 0 0 0 91 0 0 0 0 0 % T
% Val: 0 0 0 0 19 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 91 0 0 0 % W
% Tyr: 0 10 0 0 0 0 91 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _