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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIN1L
All Species:
17.58
Human Site:
S41
Identified Species:
32.22
UniProt:
O15428
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15428
NP_006212
100
11021
S41
W
E
R
P
S
G
N
S
S
S
G
G
K
I
W
Chimpanzee
Pan troglodytes
XP_001161914
174
19574
S41
W
E
R
P
S
G
N
S
S
S
G
G
K
N
G
Rhesus Macaque
Macaca mulatta
XP_001099116
145
16071
S41
W
E
R
P
S
G
N
S
S
S
G
G
K
N
G
Dog
Lupus familis
XP_542080
163
18285
S41
W
E
R
P
S
G
N
S
S
S
G
S
K
N
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9QUR7
165
18352
S41
W
E
R
P
S
G
G
S
T
V
G
G
S
S
K
Rat
Rattus norvegicus
NP_001100171
165
18314
S41
W
E
R
P
S
G
G
S
T
V
G
G
G
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089028
159
17622
G41
W
E
R
P
T
A
G
G
K
N
G
Q
G
D
P
Zebra Danio
Brachydanio rerio
NP_957042
159
17688
G41
W
E
R
P
S
G
S
G
A
D
G
A
G
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54353
166
18358
A41
W
D
Q
P
T
E
P
A
K
K
A
G
G
G
S
Honey Bee
Apis mellifera
XP_624205
162
18033
A40
W
D
R
P
D
K
P
A
D
P
S
G
N
N
K
Nematode Worm
Caenorhab. elegans
NP_494393
168
19158
A40
W
E
R
P
D
E
S
A
F
G
K
G
S
E
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22696
170
19386
N45
W
E
E
P
E
G
T
N
K
D
Q
L
H
K
H
Red Bread Mold
Neurospora crassa
O60045
182
20596
D43
W
E
P
P
S
G
T
D
V
D
K
L
K
I
Y
Conservation
Percent
Protein Identity:
100
43.6
47.5
43.5
N.A.
41.2
41.8
N.A.
N.A.
N.A.
35.2
33.9
N.A.
28.3
30.2
26.7
N.A.
Protein Similarity:
100
47.7
52.4
47.2
N.A.
47.2
46
N.A.
N.A.
N.A.
45.2
46.5
N.A.
39.7
42.5
38
N.A.
P-Site Identity:
100
86.6
86.6
80
N.A.
60
60
N.A.
N.A.
N.A.
33.3
46.6
N.A.
20
26.6
33.3
N.A.
P-Site Similarity:
100
86.6
86.6
80
N.A.
66.6
66.6
N.A.
N.A.
N.A.
46.6
60
N.A.
46.6
40
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.1
23.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
32.9
34
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
46.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
24
8
0
8
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
0
0
16
0
0
8
8
24
0
0
0
16
0
% D
% Glu:
0
85
8
0
8
16
0
0
0
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
70
24
16
0
8
62
62
31
8
24
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% I
% Lys:
0
0
0
0
0
8
0
0
24
8
16
0
39
8
24
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
31
8
0
8
0
0
8
31
0
% N
% Pro:
0
0
8
100
0
0
16
0
0
8
0
0
0
0
8
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
8
8
0
0
0
% Q
% Arg:
0
0
77
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
62
0
16
47
31
31
8
8
16
16
8
% S
% Thr:
0
0
0
0
16
0
16
0
16
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
8
16
0
0
0
0
8
% V
% Trp:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _