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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIN1L
All Species:
13.33
Human Site:
S58
Identified Species:
24.44
UniProt:
O15428
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15428
NP_006212
100
11021
S58
E
P
A
R
V
R
R
S
H
L
L
V
K
P
V
Chimpanzee
Pan troglodytes
XP_001161914
174
19574
S58
E
P
A
R
V
R
C
S
H
L
L
V
K
H
S
Rhesus Macaque
Macaca mulatta
XP_001099116
145
16071
S58
E
P
A
R
V
R
C
S
H
L
L
V
K
H
S
Dog
Lupus familis
XP_542080
163
18285
S58
E
P
T
R
V
R
C
S
H
L
L
V
K
H
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9QUR7
165
18352
R58
Q
G
E
P
A
K
V
R
C
S
H
L
L
V
K
Rat
Rattus norvegicus
NP_001100171
165
18314
R58
Q
G
E
P
A
R
V
R
C
S
H
L
L
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089028
159
17622
V58
V
R
C
S
H
L
L
V
K
H
N
Q
S
R
R
Zebra Danio
Brachydanio rerio
NP_957042
159
17688
V58
V
R
C
S
H
L
L
V
K
H
S
Q
S
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54353
166
18358
V58
G
G
D
A
P
D
E
V
H
C
L
H
L
L
V
Honey Bee
Apis mellifera
XP_624205
162
18033
S57
G
P
E
E
V
Q
C
S
H
L
L
V
K
H
S
Nematode Worm
Caenorhab. elegans
NP_494393
168
19158
V57
V
Q
C
L
H
L
L
V
K
H
D
G
S
R
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22696
170
19386
C62
D
H
P
V
R
V
R
C
L
H
I
L
I
K
H
Red Bread Mold
Neurospora crassa
O60045
182
20596
Q60
K
Y
H
S
P
T
S
Q
Q
Q
Q
Q
Q
Q
Q
Conservation
Percent
Protein Identity:
100
43.6
47.5
43.5
N.A.
41.2
41.8
N.A.
N.A.
N.A.
35.2
33.9
N.A.
28.3
30.2
26.7
N.A.
Protein Similarity:
100
47.7
52.4
47.2
N.A.
47.2
46
N.A.
N.A.
N.A.
45.2
46.5
N.A.
39.7
42.5
38
N.A.
P-Site Identity:
100
80
80
73.3
N.A.
0
6.6
N.A.
N.A.
N.A.
0
0
N.A.
20
53.3
0
N.A.
P-Site Similarity:
100
80
80
73.3
N.A.
20
20
N.A.
N.A.
N.A.
0
0
N.A.
20
60
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.1
23.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
32.9
34
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
24
8
16
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
24
0
0
0
31
8
16
8
0
0
0
0
0
% C
% Asp:
8
0
8
0
0
8
0
0
0
0
8
0
0
0
0
% D
% Glu:
31
0
24
8
0
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
16
24
0
0
0
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
8
8
0
24
0
0
0
47
31
16
8
0
31
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% I
% Lys:
8
0
0
0
0
8
0
0
24
0
0
0
39
8
16
% K
% Leu:
0
0
0
8
0
24
24
0
8
39
47
24
24
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% N
% Pro:
0
39
8
16
16
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
16
8
0
0
0
8
0
8
8
8
8
24
8
8
8
% Q
% Arg:
0
16
0
31
8
39
16
16
0
0
0
0
0
24
16
% R
% Ser:
0
0
0
24
0
0
8
39
0
16
8
0
24
0
31
% S
% Thr:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% T
% Val:
24
0
0
8
39
8
16
31
0
0
0
39
0
16
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _