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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIN1L
All Species:
34.24
Human Site:
Y24
Identified Species:
62.78
UniProt:
O15428
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15428
NP_006212
100
11021
Y24
R
P
S
G
R
G
Y
Y
F
N
H
I
T
N
P
Chimpanzee
Pan troglodytes
XP_001161914
174
19574
Y24
R
S
S
G
R
V
Y
Y
F
N
H
I
T
N
A
Rhesus Macaque
Macaca mulatta
XP_001099116
145
16071
Y24
R
S
S
G
R
V
Y
Y
F
N
H
I
T
N
A
Dog
Lupus familis
XP_542080
163
18285
Y24
R
S
S
G
R
V
Y
Y
F
N
H
I
T
N
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9QUR7
165
18352
Y24
R
S
S
G
R
V
Y
Y
F
N
H
I
T
N
A
Rat
Rattus norvegicus
NP_001100171
165
18314
Y24
R
S
S
G
R
V
Y
Y
F
N
H
I
T
N
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089028
159
17622
Y24
R
S
S
G
R
V
Y
Y
F
N
H
M
T
N
A
Zebra Danio
Brachydanio rerio
NP_957042
159
17688
Y24
R
S
S
G
R
V
Y
Y
F
N
H
I
T
N
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54353
166
18358
Y24
R
S
T
G
M
S
Y
Y
L
N
M
Y
T
K
E
Honey Bee
Apis mellifera
XP_624205
162
18033
Y23
R
S
T
G
Q
H
Y
Y
L
N
I
Y
T
K
E
Nematode Worm
Caenorhab. elegans
NP_494393
168
19158
Y23
R
S
N
D
R
V
Y
Y
F
N
T
A
T
G
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22696
170
19386
F28
K
S
K
K
R
E
Y
F
F
N
P
E
T
K
H
Red Bread Mold
Neurospora crassa
O60045
182
20596
Y26
Q
S
K
N
L
P
Y
Y
F
N
S
A
T
K
T
Conservation
Percent
Protein Identity:
100
43.6
47.5
43.5
N.A.
41.2
41.8
N.A.
N.A.
N.A.
35.2
33.9
N.A.
28.3
30.2
26.7
N.A.
Protein Similarity:
100
47.7
52.4
47.2
N.A.
47.2
46
N.A.
N.A.
N.A.
45.2
46.5
N.A.
39.7
42.5
38
N.A.
P-Site Identity:
100
80
80
80
N.A.
80
80
N.A.
N.A.
N.A.
73.3
80
N.A.
40
40
46.6
N.A.
P-Site Similarity:
100
80
80
80
N.A.
80
80
N.A.
N.A.
N.A.
80
80
N.A.
46.6
53.3
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.1
23.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
32.9
34
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
54
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
16
% E
% Phe:
0
0
0
0
0
0
0
8
85
0
0
0
0
0
0
% F
% Gly:
0
0
0
77
0
8
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
62
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
54
0
0
0
% I
% Lys:
8
0
16
8
0
0
0
0
0
0
0
0
0
31
0
% K
% Leu:
0
0
0
0
8
0
0
0
16
0
0
0
0
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
8
8
0
0
0
% M
% Asn:
0
0
8
8
0
0
0
0
0
100
0
0
0
62
0
% N
% Pro:
0
8
0
0
0
8
0
0
0
0
8
0
0
0
8
% P
% Gln:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
85
0
0
0
77
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
93
62
0
0
8
0
0
0
0
8
0
0
0
0
% S
% Thr:
0
0
16
0
0
0
0
0
0
0
8
0
100
0
8
% T
% Val:
0
0
0
0
0
62
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
100
93
0
0
0
16
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _