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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC31A1 All Species: 39.7
Human Site: S105 Identified Species: 62.38
UniProt: O15431 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15431 NP_001850.1 190 21091 S105 Q V S I R Y N S M P V P G P N
Chimpanzee Pan troglodytes XP_001150644 116 12664 S31 S H G G G D S S M M M M P M T
Rhesus Macaque Macaca mulatta XP_001103110 190 21092 S105 Q V S I R Y N S M P V P G P N
Dog Lupus familis XP_538800 244 27467 S159 Q V S I R Y N S M P V P G P N
Cat Felis silvestris
Mouse Mus musculus Q8K211 196 21942 S111 Q V S I R Y N S M P V P G P N
Rat Rattus norvegicus Q9JK41 187 21110 S102 Q V S I R Y N S M P V P G P N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506031 189 21112 S104 Q V S I R Y N S M P V P G P N
Chicken Gallus gallus XP_415542 214 23396 S129 Q V S I R Y N S M P V P G P N
Frog Xenopus laevis NP_001086371 187 20492 S102 H V S I R Y N S M P V P G P N
Zebra Danio Brachydanio rerio NP_991280 188 20747 S103 Q V N V R Y N S M P V P G S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572336 231 25628 R146 R P V T G P Q R N P E A P R I
Honey Bee Apis mellifera XP_623615 223 25531 V138 T M P Q E K N V V A E D N R V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785308 207 23066 S122 V V N V R Y H S Q Q I S K G S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39065 170 18381 H86 V L T E W L A H S S L L R G S
Baker's Yeast Sacchar. cerevisiae P38865 189 21633 K103 A Y L Y E Y L K Y C V H K R Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 61 98.9 70.9 N.A. 87.2 88.9 N.A. 86.8 71.9 78.9 70.5 N.A. 41.1 38.5 N.A. 50.7
Protein Similarity: 100 61 98.9 73.7 N.A. 90.8 91.5 N.A. 90.5 77.5 87.8 80 N.A. 54.1 52.9 N.A. 64.7
P-Site Identity: 100 13.3 100 100 N.A. 100 100 N.A. 100 100 93.3 73.3 N.A. 6.6 6.6 N.A. 26.6
P-Site Similarity: 100 26.6 100 100 N.A. 100 100 N.A. 100 100 93.3 93.3 N.A. 13.3 20 N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. 27.8 20 N.A.
Protein Similarity: N.A. N.A. N.A. 41 42.6 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 0 0 7 0 0 7 0 7 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 7 0 0 0 0 0 7 0 0 7 % D
% Glu: 0 0 0 7 14 0 0 0 0 0 14 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 7 7 14 0 0 0 0 0 0 0 60 14 0 % G
% His: 7 7 0 0 0 0 7 7 0 0 0 7 0 0 0 % H
% Ile: 0 0 0 54 0 0 0 0 0 0 7 0 0 0 7 % I
% Lys: 0 0 0 0 0 7 0 7 0 0 0 0 14 0 0 % K
% Leu: 0 7 7 0 0 7 7 0 0 0 7 7 0 0 0 % L
% Met: 0 7 0 0 0 0 0 0 67 7 7 7 0 7 0 % M
% Asn: 0 0 14 0 0 0 67 0 7 0 0 0 7 0 54 % N
% Pro: 0 7 7 0 0 7 0 0 0 67 0 60 14 54 0 % P
% Gln: 54 0 0 7 0 0 7 0 7 7 0 0 0 0 7 % Q
% Arg: 7 0 0 0 67 0 0 7 0 0 0 0 7 20 0 % R
% Ser: 7 0 54 0 0 0 7 74 7 7 0 7 0 7 14 % S
% Thr: 7 0 7 7 0 0 0 0 0 0 0 0 0 0 7 % T
% Val: 14 67 7 14 0 0 0 7 7 0 67 0 0 0 7 % V
% Trp: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 7 0 74 0 0 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _