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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC31A1 All Species: 36.36
Human Site: T122 Identified Species: 57.14
UniProt: O15431 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15431 NP_001850.1 190 21091 T122 I L M E T H K T V G Q Q M L S
Chimpanzee Pan troglodytes XP_001150644 116 12664 L48 F G F K N V E L L F S G L V I
Rhesus Macaque Macaca mulatta XP_001103110 190 21092 T122 I L M E T H K T V G Q Q M L S
Dog Lupus familis XP_538800 244 27467 T176 I L M E T H K T V G Q Q M L S
Cat Felis silvestris
Mouse Mus musculus Q8K211 196 21942 T128 I L M E T H K T V G Q Q M L S
Rat Rattus norvegicus Q9JK41 187 21110 T119 I L M E T H K T V G Q Q M L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506031 189 21112 T121 I L M E T H K T V G Q Q M L S
Chicken Gallus gallus XP_415542 214 23396 T146 I L M E T H K T V G Q Q M L S
Frog Xenopus laevis NP_001086371 187 20492 T119 I L M E T H K T V G Q R M L S
Zebra Danio Brachydanio rerio NP_991280 188 20747 T120 V L M E T H K T V G Q R M L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572336 231 25628 P163 P A A A A P S P V Q P S M L S
Honey Bee Apis mellifera XP_623615 223 25531 K155 M V G E V I H K Q P P T M L S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785308 207 23066 A139 F L T E T H N A G E A Q L L S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39065 170 18381 G103 D S A N R A A G L I Q T A V Y
Baker's Yeast Sacchar. cerevisiae P38865 189 21633 R120 Q R V L L P N R S L T K I N Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 61 98.9 70.9 N.A. 87.2 88.9 N.A. 86.8 71.9 78.9 70.5 N.A. 41.1 38.5 N.A. 50.7
Protein Similarity: 100 61 98.9 73.7 N.A. 90.8 91.5 N.A. 90.5 77.5 87.8 80 N.A. 54.1 52.9 N.A. 64.7
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 100 100 93.3 86.6 N.A. 26.6 26.6 N.A. 46.6
P-Site Similarity: 100 33.3 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 26.6 40 N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. 27.8 20 N.A.
Protein Similarity: N.A. N.A. N.A. 41 42.6 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 14 7 7 7 7 7 0 0 7 0 7 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 74 0 0 7 0 0 7 0 0 0 0 0 % E
% Phe: 14 0 7 0 0 0 0 0 0 7 0 0 0 0 0 % F
% Gly: 0 7 7 0 0 0 0 7 7 60 0 7 0 0 0 % G
% His: 0 0 0 0 0 67 7 0 0 0 0 0 0 0 0 % H
% Ile: 54 0 0 0 0 7 0 0 0 7 0 0 7 0 7 % I
% Lys: 0 0 0 7 0 0 60 7 0 0 0 7 0 0 0 % K
% Leu: 0 67 0 7 7 0 0 7 14 7 0 0 14 80 0 % L
% Met: 7 0 60 0 0 0 0 0 0 0 0 0 74 0 0 % M
% Asn: 0 0 0 7 7 0 14 0 0 0 0 0 0 7 0 % N
% Pro: 7 0 0 0 0 14 0 7 0 7 14 0 0 0 0 % P
% Gln: 7 0 0 0 0 0 0 0 7 7 67 54 0 0 7 % Q
% Arg: 0 7 0 0 7 0 0 7 0 0 0 14 0 0 0 % R
% Ser: 0 7 0 0 0 0 7 0 7 0 7 7 0 0 80 % S
% Thr: 0 0 7 0 67 0 0 60 0 0 7 14 0 0 0 % T
% Val: 7 7 7 0 7 7 0 0 67 0 0 0 0 14 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _