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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCC3 All Species: 26.06
Human Site: S1409 Identified Species: 52.12
UniProt: O15438 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15438 NP_003777.2 1527 169343 S1409 S H L H T F V S S Q P A G L D
Chimpanzee Pan troglodytes XP_001158914 1538 170274 D1421 K S R I L V L D E A T A A I D
Rhesus Macaque Macaca mulatta XP_001094709 1612 178491 S1494 S H L H T F V S S Q P A G L D
Dog Lupus familis XP_548204 1523 168842 S1405 S H L H T F V S S Q P A G L D
Cat Felis silvestris
Mouse Mus musculus B2RX12 1523 169105 S1405 S H L N T F V S S Q P A G L D
Rat Rattus norvegicus O88563 1522 168960 S1404 S H L S A F V S S Q P T G L D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517193 1537 172363 S1419 A H L K N F V S L L P D K L N
Chicken Gallus gallus Q5F364 1525 170953 S1407 A H L K N F V S S L P D K L N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001341895 1518 169232 S1400 A H L K T F V S G L P D K L N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91660 1290 143990 Q1176 G T N F S V G Q R Q L V C L A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C8H1 1495 168085 D1355 A H I K D V I D R N P F G L D
Baker's Yeast Sacchar. cerevisiae P39109 1515 171103 L1392 S H L K E H V L S M S N D G L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.2 90.4 84.5 N.A. 80.6 78 N.A. 56.8 58.1 N.A. 56.9 N.A. 29.6 N.A. N.A. N.A.
Protein Similarity: 100 87.2 92.4 91.6 N.A. 89.1 87.2 N.A. 73.9 75.5 N.A. 75.1 N.A. 47.3 N.A. N.A. N.A.
P-Site Identity: 100 13.3 100 100 N.A. 93.3 80 N.A. 46.6 53.3 N.A. 53.3 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 100 80 N.A. 60 66.6 N.A. 66.6 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 34.9 38.4 N.A.
Protein Similarity: N.A. N.A. N.A. 54.3 58.4 N.A.
P-Site Identity: N.A. N.A. N.A. 33.3 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 34 0 0 0 9 0 0 0 0 9 0 42 9 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % C
% Asp: 0 0 0 0 9 0 0 17 0 0 0 25 9 0 59 % D
% Glu: 0 0 0 0 9 0 0 0 9 0 0 0 0 0 0 % E
% Phe: 0 0 0 9 0 67 0 0 0 0 0 9 0 0 0 % F
% Gly: 9 0 0 0 0 0 9 0 9 0 0 0 50 9 0 % G
% His: 0 84 0 25 0 9 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 9 9 0 0 9 0 0 0 0 0 0 9 0 % I
% Lys: 9 0 0 42 0 0 0 0 0 0 0 0 25 0 0 % K
% Leu: 0 0 75 0 9 0 9 9 9 25 9 0 0 84 9 % L
% Met: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % M
% Asn: 0 0 9 9 17 0 0 0 0 9 0 9 0 0 25 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 75 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 9 0 50 0 0 0 0 0 % Q
% Arg: 0 0 9 0 0 0 0 0 17 0 0 0 0 0 0 % R
% Ser: 50 9 0 9 9 0 0 67 59 0 9 0 0 0 0 % S
% Thr: 0 9 0 0 42 0 0 0 0 0 9 9 0 0 0 % T
% Val: 0 0 0 0 0 25 75 0 0 0 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _