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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCC3 All Species: 16.36
Human Site: S17 Identified Species: 32.73
UniProt: O15438 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15438 NP_003777.2 1527 169343 S17 L G S K F W D S N L S V H T E
Chimpanzee Pan troglodytes XP_001158914 1538 170274 S70 G T V R G W D S N L S V H T E
Rhesus Macaque Macaca mulatta XP_001094709 1612 178491 S103 L G S K F W D S N L S V H T D
Dog Lupus familis XP_548204 1523 168842 H17 W D S N L S V H T D N P D L T
Cat Felis silvestris
Mouse Mus musculus B2RX12 1523 169105 S17 L G S K F W D S N L S I Y T N
Rat Rattus norvegicus O88563 1522 168960 S17 L G S K F W D S N L T V Y T N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517193 1537 172363 W30 S S V P F W D W N V T W H T Y
Chicken Gallus gallus Q5F364 1525 170953 W18 A S E P F W D W N L T W H T E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001341895 1518 169232 W18 G S D P L W D W N R T W Q T Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91660 1290 143990
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C8H1 1495 168085 W18 K P I A E G F W E K T P D G A
Baker's Yeast Sacchar. cerevisiae P39109 1515 171103 E17 C K L C R S P E G F G P I S F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.2 90.4 84.5 N.A. 80.6 78 N.A. 56.8 58.1 N.A. 56.9 N.A. 29.6 N.A. N.A. N.A.
Protein Similarity: 100 87.2 92.4 91.6 N.A. 89.1 87.2 N.A. 73.9 75.5 N.A. 75.1 N.A. 47.3 N.A. N.A. N.A.
P-Site Identity: 100 66.6 93.3 6.6 N.A. 80 80 N.A. 40 53.3 N.A. 26.6 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 73.3 100 13.3 N.A. 93.3 93.3 N.A. 53.3 60 N.A. 33.3 N.A. 0 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 34.9 38.4 N.A.
Protein Similarity: N.A. N.A. N.A. 54.3 58.4 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 9 0 0 0 0 0 0 0 0 0 0 9 % A
% Cys: 9 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 9 0 0 0 67 0 0 9 0 0 17 0 9 % D
% Glu: 0 0 9 0 9 0 0 9 9 0 0 0 0 0 25 % E
% Phe: 0 0 0 0 50 0 9 0 0 9 0 0 0 0 9 % F
% Gly: 17 34 0 0 9 9 0 0 9 0 9 0 0 9 0 % G
% His: 0 0 0 0 0 0 0 9 0 0 0 0 42 0 0 % H
% Ile: 0 0 9 0 0 0 0 0 0 0 0 9 9 0 0 % I
% Lys: 9 9 0 34 0 0 0 0 0 9 0 0 0 0 0 % K
% Leu: 34 0 9 0 17 0 0 0 0 50 0 0 0 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 0 0 0 67 0 9 0 0 0 17 % N
% Pro: 0 9 0 25 0 0 9 0 0 0 0 25 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % Q
% Arg: 0 0 0 9 9 0 0 0 0 9 0 0 0 0 0 % R
% Ser: 9 25 42 0 0 17 0 42 0 0 34 0 0 9 0 % S
% Thr: 0 9 0 0 0 0 0 0 9 0 42 0 0 67 9 % T
% Val: 0 0 17 0 0 0 9 0 0 9 0 34 0 0 0 % V
% Trp: 9 0 0 0 0 67 0 34 0 0 0 25 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 17 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _