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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCC3
All Species:
29.09
Human Site:
S249
Identified Species:
58.18
UniProt:
O15438
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15438
NP_003777.2
1527
169343
S249
S
L
K
E
E
D
R
S
Q
M
V
V
Q
Q
L
Chimpanzee
Pan troglodytes
XP_001158914
1538
170274
S302
S
L
K
E
E
D
R
S
Q
M
V
V
Q
Q
L
Rhesus Macaque
Macaca mulatta
XP_001094709
1612
178491
S335
S
L
K
E
E
D
R
S
Q
M
V
V
Q
Q
L
Dog
Lupus familis
XP_548204
1523
168842
S244
S
L
K
E
D
D
C
S
Q
K
V
V
N
R
L
Cat
Felis silvestris
Mouse
Mus musculus
B2RX12
1523
169105
S249
S
L
S
E
E
D
C
S
H
K
V
V
Q
R
L
Rat
Rattus norvegicus
O88563
1522
168960
S249
S
L
S
E
E
D
C
S
H
K
V
V
Q
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517193
1537
172363
S262
S
L
N
R
E
D
T
S
D
Q
V
V
P
V
L
Chicken
Gallus gallus
Q5F364
1525
170953
S250
S
L
N
K
E
D
T
S
E
E
I
V
P
G
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001341895
1518
169232
S250
S
L
N
N
E
D
K
S
E
R
V
V
P
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91660
1290
143990
Y125
D
A
A
N
A
G
F
Y
Y
A
V
A
Q
I
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8H1
1495
168085
M243
S
G
I
Y
F
S
W
M
T
P
L
M
Q
L
G
Baker's Yeast
Sacchar. cerevisiae
P39109
1515
171103
P247
E
A
D
L
Y
K
L
P
R
N
F
S
S
E
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.2
90.4
84.5
N.A.
80.6
78
N.A.
56.8
58.1
N.A.
56.9
N.A.
29.6
N.A.
N.A.
N.A.
Protein Similarity:
100
87.2
92.4
91.6
N.A.
89.1
87.2
N.A.
73.9
75.5
N.A.
75.1
N.A.
47.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
66.6
N.A.
66.6
66.6
N.A.
53.3
46.6
N.A.
60
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
73.3
73.3
N.A.
53.3
66.6
N.A.
73.3
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.9
38.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.3
58.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
9
0
9
0
0
0
0
9
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
25
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
9
0
9
75
0
0
9
0
0
0
0
0
0
% D
% Glu:
9
0
0
50
67
0
0
0
17
9
0
0
0
9
9
% E
% Phe:
0
0
0
0
9
0
9
0
0
0
9
0
0
0
0
% F
% Gly:
0
9
0
0
0
9
0
0
0
0
0
0
0
9
9
% G
% His:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
9
0
0
9
0
% I
% Lys:
0
0
34
9
0
9
9
0
0
25
0
0
0
0
0
% K
% Leu:
0
75
0
9
0
0
9
0
0
0
9
0
0
9
75
% L
% Met:
0
0
0
0
0
0
0
9
0
25
0
9
0
0
0
% M
% Asn:
0
0
25
17
0
0
0
0
0
9
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
9
0
9
0
0
25
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
34
9
0
0
59
34
0
% Q
% Arg:
0
0
0
9
0
0
25
0
9
9
0
0
0
25
0
% R
% Ser:
84
0
17
0
0
9
0
75
0
0
0
9
9
0
0
% S
% Thr:
0
0
0
0
0
0
17
0
9
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
75
75
0
9
9
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
9
0
0
9
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _