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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCC4 All Species: 41.82
Human Site: S199 Identified Species: 76.67
UniProt: O15439 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15439 NP_001098985.1 1325 149527 S199 G Q I V N L L S N D V N K F D
Chimpanzee Pan troglodytes XP_001137085 1325 149612 S199 G Q I V N L L S N D V N K F D
Rhesus Macaque Macaca mulatta XP_001084757 859 96617
Dog Lupus familis XP_542642 1516 170242 S390 G Q I V N L L S N D V N K F D
Cat Felis silvestris
Mouse Mus musculus O35379 1528 171166 S429 G E I V N L M S V D A Q R F M
Rat Rattus norvegicus Q8CG09 1532 171475 S429 G E I V N L M S V D A Q R F M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512380 1314 148498 S186 G Q I V N L L S N D V N K F D
Chicken Gallus gallus Q5F364 1525 170953 S427 G E I V N L M S V D A Q R F M
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001007039 1327 149226 S199 G Q I V N L L S N D V N K F D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91660 1290 143990 S188 G H V V N L I S N D I P R L D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001190458 1362 153036 S186 G K L V N I L S S D V N R F D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42093 1623 182111 T404 G K I T N L M T T D A E S L Q
Baker's Yeast Sacchar. cerevisiae P39109 1515 171103 S410 G D I V N L M S V D V Q K L Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 62.9 78 N.A. 33.1 32 N.A. 81.3 33.8 N.A. 69.3 N.A. 40.9 N.A. N.A. 49.6
Protein Similarity: 100 99.8 63.9 82.4 N.A. 53.6 52 N.A. 89.6 52.9 N.A. 82.8 N.A. 62.7 N.A. N.A. 67.4
P-Site Identity: 100 100 0 100 N.A. 53.3 53.3 N.A. 100 53.3 N.A. 100 N.A. 53.3 N.A. N.A. 66.6
P-Site Similarity: 100 100 0 100 N.A. 73.3 73.3 N.A. 100 73.3 N.A. 100 N.A. 80 N.A. N.A. 100
Percent
Protein Identity: N.A. N.A. N.A. 31.1 33.5 N.A.
Protein Similarity: N.A. N.A. N.A. 48.5 51.6 N.A.
P-Site Identity: N.A. N.A. N.A. 33.3 60 N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 31 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 0 0 93 0 0 0 0 54 % D
% Glu: 0 24 0 0 0 0 0 0 0 0 0 8 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 70 0 % F
% Gly: 93 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 77 0 0 8 8 0 0 0 8 0 0 0 0 % I
% Lys: 0 16 0 0 0 0 0 0 0 0 0 0 47 0 0 % K
% Leu: 0 0 8 0 0 85 47 0 0 0 0 0 0 24 0 % L
% Met: 0 0 0 0 0 0 39 0 0 0 0 0 0 0 24 % M
% Asn: 0 0 0 0 93 0 0 0 47 0 0 47 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % P
% Gln: 0 39 0 0 0 0 0 0 0 0 0 31 0 0 16 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 39 0 0 % R
% Ser: 0 0 0 0 0 0 0 85 8 0 0 0 8 0 0 % S
% Thr: 0 0 0 8 0 0 0 8 8 0 0 0 0 0 0 % T
% Val: 0 0 8 85 0 0 0 0 31 0 54 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _