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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCC4 All Species: 24.24
Human Site: S79 Identified Species: 44.44
UniProt: O15439 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15439 NP_001098985.1 1325 149527 S79 E N D A Q K P S L T R A I I K
Chimpanzee Pan troglodytes XP_001137085 1325 149612 S79 E N D A Q K P S L T R A I I K
Rhesus Macaque Macaca mulatta XP_001084757 859 96617
Dog Lupus familis XP_542642 1516 170242 S270 K S D A R K P S L T K A I I K
Cat Felis silvestris
Mouse Mus musculus O35379 1528 171166 D309 I V K S P H K D R E P S L F K
Rat Rattus norvegicus Q8CG09 1532 171475 D309 I V K S S H K D R D P S L F K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512380 1314 148498 S66 K K E A R K P S L T K A I I R
Chicken Gallus gallus Q5F364 1525 170953 S307 I I K P S Q R S S E A S L S K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001007039 1327 149226 K79 A K E L K T P K L T K A I I R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91660 1290 143990 S71 K N D G R S P S L V R A L L R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001190458 1362 153036 S68 E N H E K K P S L L R A L I K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42093 1623 182111 Q284 H S W D K E L Q K P Q P W L L
Baker's Yeast Sacchar. cerevisiae P39109 1515 171103 S274 L K Q K S N P S L S W A I C R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 62.9 78 N.A. 33.1 32 N.A. 81.3 33.8 N.A. 69.3 N.A. 40.9 N.A. N.A. 49.6
Protein Similarity: 100 99.8 63.9 82.4 N.A. 53.6 52 N.A. 89.6 52.9 N.A. 82.8 N.A. 62.7 N.A. N.A. 67.4
P-Site Identity: 100 100 0 73.3 N.A. 6.6 6.6 N.A. 60 13.3 N.A. 40 N.A. 46.6 N.A. N.A. 66.6
P-Site Similarity: 100 100 0 100 N.A. 26.6 26.6 N.A. 93.3 33.3 N.A. 66.6 N.A. 80 N.A. N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. 31.1 33.5 N.A.
Protein Similarity: N.A. N.A. N.A. 48.5 51.6 N.A.
P-Site Identity: N.A. N.A. N.A. 0 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 31 0 0 0 0 0 0 8 62 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 0 0 31 8 0 0 0 16 0 8 0 0 0 0 0 % D
% Glu: 24 0 16 8 0 8 0 0 0 16 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 16 0 % F
% Gly: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 8 0 8 0 0 16 0 0 0 0 0 0 0 0 0 % H
% Ile: 24 8 0 0 0 0 0 0 0 0 0 0 47 47 0 % I
% Lys: 24 24 24 8 24 39 16 8 8 0 24 0 0 0 54 % K
% Leu: 8 0 0 8 0 0 8 0 62 8 0 0 39 16 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 31 0 0 0 8 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 8 8 0 62 0 0 8 16 8 0 0 0 % P
% Gln: 0 0 8 0 16 8 0 8 0 0 8 0 0 0 0 % Q
% Arg: 0 0 0 0 24 0 8 0 16 0 31 0 0 0 31 % R
% Ser: 0 16 0 16 24 8 0 62 8 8 0 24 0 8 0 % S
% Thr: 0 0 0 0 0 8 0 0 0 39 0 0 0 0 0 % T
% Val: 0 16 0 0 0 0 0 0 0 8 0 0 0 0 0 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 8 0 8 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _