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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCC4
All Species:
17.27
Human Site:
T275
Identified Species:
31.67
UniProt:
O15439
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15439
NP_001098985.1
1325
149527
T275
F
T
D
A
R
I
R
T
M
N
E
V
I
T
G
Chimpanzee
Pan troglodytes
XP_001137085
1325
149612
T275
F
T
D
A
R
I
R
T
M
N
E
V
I
T
G
Rhesus Macaque
Macaca mulatta
XP_001084757
859
96617
Dog
Lupus familis
XP_542642
1516
170242
T466
F
T
D
V
R
I
R
T
M
N
E
V
I
T
G
Cat
Felis silvestris
Mouse
Mus musculus
O35379
1528
171166
L505
S
K
D
N
R
I
K
L
M
N
E
I
L
N
G
Rat
Rattus norvegicus
Q8CG09
1532
171475
L505
S
K
D
N
R
I
K
L
M
N
E
I
L
N
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512380
1314
148498
T262
F
T
D
V
R
I
R
T
M
N
E
V
I
T
G
Chicken
Gallus gallus
Q5F364
1525
170953
L503
S
K
D
N
R
I
K
L
M
N
E
I
L
N
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007039
1327
149226
T275
L
T
D
S
R
I
R
T
M
N
E
V
V
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91660
1290
143990
M264
R
T
D
N
R
I
R
M
V
N
E
I
I
S
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190458
1362
153036
I262
L
T
D
E
R
V
R
I
M
N
E
I
I
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42093
1623
182111
L480
R
T
D
K
R
I
G
L
M
N
E
V
L
A
A
Baker's Yeast
Sacchar. cerevisiae
P39109
1515
171103
V486
Y
K
D
E
R
T
R
V
I
S
E
I
L
N
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
62.9
78
N.A.
33.1
32
N.A.
81.3
33.8
N.A.
69.3
N.A.
40.9
N.A.
N.A.
49.6
Protein Similarity:
100
99.8
63.9
82.4
N.A.
53.6
52
N.A.
89.6
52.9
N.A.
82.8
N.A.
62.7
N.A.
N.A.
67.4
P-Site Identity:
100
100
0
93.3
N.A.
46.6
46.6
N.A.
93.3
46.6
N.A.
73.3
N.A.
53.3
N.A.
N.A.
60
P-Site Similarity:
100
100
0
93.3
N.A.
66.6
66.6
N.A.
93.3
66.6
N.A.
93.3
N.A.
73.3
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.1
33.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.5
51.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
16
0
0
0
0
0
0
0
0
0
8
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
93
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
16
0
0
0
0
0
0
93
0
0
0
0
% E
% Phe:
31
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
70
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
77
0
8
8
0
0
47
47
0
0
% I
% Lys:
0
31
0
8
0
0
24
0
0
0
0
0
0
0
0
% K
% Leu:
16
0
0
0
0
0
0
31
0
0
0
0
39
0
0
% L
% Met:
0
0
0
0
0
0
0
8
77
0
0
0
0
0
0
% M
% Asn:
0
0
0
31
0
0
0
0
0
85
0
0
0
31
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
16
0
0
0
93
0
62
0
0
0
0
0
0
0
0
% R
% Ser:
24
0
0
8
0
0
0
0
0
8
0
0
0
24
0
% S
% Thr:
0
62
0
0
0
8
0
39
0
0
0
0
0
31
0
% T
% Val:
0
0
0
16
0
8
0
8
8
0
0
47
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _