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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCC4 All Species: 16.36
Human Site: Y1027 Identified Species: 30
UniProt: O15439 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15439 NP_001098985.1 1325 149527 Y1027 E K E A P W E Y Q K R P P P A
Chimpanzee Pan troglodytes XP_001137085 1325 149612 Y1027 E K E A P W E Y Q K R P P P A
Rhesus Macaque Macaca mulatta XP_001084757 859 96617 H583 L C I C Q T L H E K I T I L V
Dog Lupus familis XP_542642 1516 170242 Y1218 E K E A P W E Y Q K R P P P T
Cat Felis silvestris
Mouse Mus musculus O35379 1528 171166 S1248 L N W L V R M S S E M E T N I
Rat Rattus norvegicus Q8CG09 1532 171475 S1252 L N W L V R M S S E M E T N I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512380 1314 148498 S1016 E K E A P W E S K K R P P Q G
Chicken Gallus gallus Q5F364 1525 170953 T1245 L N W L V R M T S D L E T N I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001007039 1327 149226 T1035 E S E A P W E T Q K R P S P D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91660 1290 143990 E1013 E Y E S I E P E G M L E A P D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001190458 1362 153036 K1075 K P E A P L E K E K E P D A D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42093 1623 182111 I1227 P P E A P P V I E N N R P P P
Baker's Yeast Sacchar. cerevisiae P39109 1515 171103 E1234 V R M T V E V E T N I V S V E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 62.9 78 N.A. 33.1 32 N.A. 81.3 33.8 N.A. 69.3 N.A. 40.9 N.A. N.A. 49.6
Protein Similarity: 100 99.8 63.9 82.4 N.A. 53.6 52 N.A. 89.6 52.9 N.A. 82.8 N.A. 62.7 N.A. N.A. 67.4
P-Site Identity: 100 100 6.6 93.3 N.A. 0 0 N.A. 73.3 0 N.A. 73.3 N.A. 20 N.A. N.A. 40
P-Site Similarity: 100 100 20 93.3 N.A. 6.6 6.6 N.A. 80 0 N.A. 73.3 N.A. 26.6 N.A. N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. 31.1 33.5 N.A.
Protein Similarity: N.A. N.A. N.A. 48.5 51.6 N.A.
P-Site Identity: N.A. N.A. N.A. 33.3 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 54 0 0 0 0 0 0 0 0 8 8 16 % A
% Cys: 0 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 24 % D
% Glu: 47 0 62 0 0 16 47 16 24 16 8 31 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 8 0 0 8 0 0 16 0 8 0 24 % I
% Lys: 8 31 0 0 0 0 0 8 8 54 0 0 0 0 0 % K
% Leu: 31 0 0 24 0 8 8 0 0 0 16 0 0 8 0 % L
% Met: 0 0 8 0 0 0 24 0 0 8 16 0 0 0 0 % M
% Asn: 0 24 0 0 0 0 0 0 0 16 8 0 0 24 0 % N
% Pro: 8 16 0 0 54 8 8 0 0 0 0 47 39 47 8 % P
% Gln: 0 0 0 0 8 0 0 0 31 0 0 0 0 8 0 % Q
% Arg: 0 8 0 0 0 24 0 0 0 0 39 8 0 0 0 % R
% Ser: 0 8 0 8 0 0 0 24 24 0 0 0 16 0 0 % S
% Thr: 0 0 0 8 0 8 0 16 8 0 0 8 24 0 8 % T
% Val: 8 0 0 0 31 0 16 0 0 0 0 8 0 8 8 % V
% Trp: 0 0 24 0 0 39 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 24 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _