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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCC4
All Species:
16.36
Human Site:
Y1270
Identified Species:
30
UniProt:
O15439
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15439
NP_001098985.1
1325
149527
Y1270
Q
N
K
E
S
L
F
Y
K
M
V
Q
Q
L
G
Chimpanzee
Pan troglodytes
XP_001137085
1325
149612
Y1270
Q
N
K
E
S
L
F
Y
K
M
V
Q
Q
L
G
Rhesus Macaque
Macaca mulatta
XP_001084757
859
96617
I805
H
N
K
M
F
E
S
I
L
K
A
P
V
L
F
Dog
Lupus familis
XP_542642
1516
170242
Y1461
Q
N
E
E
S
L
F
Y
K
M
V
Q
Q
L
G
Cat
Felis silvestris
Mouse
Mus musculus
O35379
1528
171166
E1474
S
T
I
R
T
Q
F
E
D
C
T
V
L
T
I
Rat
Rattus norvegicus
Q8CG09
1532
171475
E1478
S
T
I
R
T
Q
F
E
D
S
T
V
L
T
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512380
1314
148498
Y1259
Q
N
K
E
S
L
F
Y
K
M
L
Q
Q
V
G
Chicken
Gallus gallus
Q5F364
1525
170953
E1471
S
T
I
K
S
Q
F
E
E
C
T
V
L
T
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007039
1327
149226
N1272
A
P
H
V
L
L
Q
N
Q
S
G
I
F
Y
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91660
1290
143990
D1235
H
R
L
H
T
I
I
D
S
D
K
V
M
V
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190458
1362
153036
P1306
R
I
I
E
F
D
E
P
Y
V
L
L
K
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42093
1623
182111
S1472
S
N
E
G
S
S
F
S
K
M
V
Q
S
T
G
Baker's Yeast
Sacchar. cerevisiae
P39109
1515
171103
K1457
E
T
I
R
T
A
F
K
D
R
T
I
L
T
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
62.9
78
N.A.
33.1
32
N.A.
81.3
33.8
N.A.
69.3
N.A.
40.9
N.A.
N.A.
49.6
Protein Similarity:
100
99.8
63.9
82.4
N.A.
53.6
52
N.A.
89.6
52.9
N.A.
82.8
N.A.
62.7
N.A.
N.A.
67.4
P-Site Identity:
100
100
20
93.3
N.A.
6.6
6.6
N.A.
86.6
13.3
N.A.
6.6
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
20
100
N.A.
13.3
13.3
N.A.
100
26.6
N.A.
13.3
N.A.
20
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.1
33.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.5
51.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
8
24
8
0
0
0
8
0
% D
% Glu:
8
0
16
39
0
8
8
24
8
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
16
0
70
0
0
0
0
0
8
0
8
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
39
% G
% His:
16
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
39
0
0
8
8
8
0
0
0
16
0
0
31
% I
% Lys:
0
0
31
8
0
0
0
8
39
8
8
0
8
0
8
% K
% Leu:
0
0
8
0
8
39
0
0
8
0
16
8
31
31
0
% L
% Met:
0
0
0
8
0
0
0
0
0
39
0
0
8
0
8
% M
% Asn:
0
47
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
8
0
0
0
8
0
0
0
% P
% Gln:
31
0
0
0
0
24
8
0
8
0
0
39
31
0
0
% Q
% Arg:
8
8
0
24
0
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
31
0
0
0
47
8
8
8
8
16
0
0
8
0
0
% S
% Thr:
0
31
0
0
31
0
0
0
0
0
31
0
0
39
0
% T
% Val:
0
0
0
8
0
0
0
0
0
8
31
31
8
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
31
8
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _