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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCC5 All Species: 9.09
Human Site: S129 Identified Species: 15.38
UniProt: O15440 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15440 NP_005679.2 1437 160660 S129 A H K K G E L S M E D V W S L
Chimpanzee Pan troglodytes XP_001163361 1366 152996 N130 V L M D I V A N I L C I I M A
Rhesus Macaque Macaca mulatta XP_001105045 1437 160671 S129 A H K K G E L S M E D V W S L
Dog Lupus familis XP_857354 1443 161421 S129 A H R K G E L S M E D V W S L
Cat Felis silvestris
Mouse Mus musculus Q9R1X5 1436 161112 L129 V H K K G E L L M E D V W P L
Rat Rattus norvegicus Q9QYM0 1436 160838 L129 V H K K G E L L M E D V W P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505267 1266 141411 E54 S Q L R I L D E G H P K G K Y
Chicken Gallus gallus Q5F364 1525 170953 I152 S L L C A T V I F R S K I M L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002665448 1385 153368 W129 Q L F L E D I W A V S Q F E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91660 1290 143990 R78 S L V R A L L R V F G W Q L G
Honey Bee Apis mellifera XP_397384 1378 156599 L131 N T H R L E I L W Q E E L N K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798419 1201 133943
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C8G9 1622 181908 L157 A L V G D M V L L N L V L S V
Baker's Yeast Sacchar. cerevisiae P53049 1477 166710 Q137 V G Y K R T I Q P N D L F K M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 43.2 99.7 95.6 N.A. 94.2 94.7 N.A. 79.3 29.5 N.A. 71.4 N.A. 30.8 41.2 N.A. 38
Protein Similarity: 100 61.7 99.7 98.1 N.A. 96.4 97.1 N.A. 83.6 48.3 N.A. 82.8 N.A. 49.2 62.2 N.A. 54.9
P-Site Identity: 100 0 100 93.3 N.A. 80 80 N.A. 0 6.6 N.A. 0 N.A. 6.6 6.6 N.A. 0
P-Site Similarity: 100 20 100 100 N.A. 80 80 N.A. 13.3 20 N.A. 20 N.A. 26.6 40 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. 29.5 30.4 N.A.
Protein Similarity: N.A. N.A. N.A. 45.1 50.1 N.A.
P-Site Identity: N.A. N.A. N.A. 20 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 29 0 0 0 15 0 8 0 8 0 0 0 0 0 8 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 0 0 8 8 8 8 0 0 0 43 0 0 0 0 % D
% Glu: 0 0 0 0 8 43 0 8 0 36 8 8 0 8 0 % E
% Phe: 0 0 8 0 0 0 0 0 8 8 0 0 15 0 0 % F
% Gly: 0 8 0 8 36 0 0 0 8 0 8 0 8 0 8 % G
% His: 0 36 8 0 0 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 0 0 0 0 15 0 22 8 8 0 0 8 15 0 0 % I
% Lys: 0 0 29 43 0 0 0 0 0 0 0 15 0 15 8 % K
% Leu: 0 36 15 8 8 15 43 29 8 8 8 8 15 8 43 % L
% Met: 0 0 8 0 0 8 0 0 36 0 0 0 0 15 8 % M
% Asn: 8 0 0 0 0 0 0 8 0 15 0 0 0 8 0 % N
% Pro: 0 0 0 0 0 0 0 0 8 0 8 0 0 15 0 % P
% Gln: 8 8 0 0 0 0 0 8 0 8 0 8 8 0 0 % Q
% Arg: 0 0 8 22 8 0 0 8 0 8 0 0 0 0 0 % R
% Ser: 22 0 0 0 0 0 0 22 0 0 15 0 0 29 8 % S
% Thr: 0 8 0 0 0 15 0 0 0 0 0 0 0 0 0 % T
% Val: 29 0 15 0 0 8 15 0 8 8 0 43 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 8 8 0 0 8 36 0 0 % W
% Tyr: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _