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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCC5 All Species: 28.18
Human Site: S1416 Identified Species: 47.69
UniProt: O15440 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15440 NP_005679.2 1437 160660 S1416 D T P S V L L S N D S S R F Y
Chimpanzee Pan troglodytes XP_001163361 1366 152996 E1350 D K P E V L A E K P D S A F A
Rhesus Macaque Macaca mulatta XP_001105045 1437 160671 S1416 D T P S V L L S N D S S R F Y
Dog Lupus familis XP_857354 1443 161421 S1422 D T P S V L L S N D S S R F Y
Cat Felis silvestris
Mouse Mus musculus Q9R1X5 1436 161112 S1415 D T P S V L L S N D S S R F Y
Rat Rattus norvegicus Q9QYM0 1436 160838 S1415 D T P S V L L S N D S S R F Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505267 1266 141411 P1252 R S K L S I I P Q E P V L F S
Chicken Gallus gallus Q5F364 1525 170953 Q1510 D S P D N L L Q A K G L F Y S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002665448 1385 153368 A1364 D E P S K L L A N E N S R F C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91660 1290 143990 S1276 V N Q S G R A S Y E G L L K I
Honey Bee Apis mellifera XP_397384 1378 156599 S1358 D A P S V L L S N S N S E F S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798419 1201 133943 S1187 V L L S D P T S I F S K M V L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C8G9 1622 181908 S1460 S S P E N L L S N G E S S F S
Baker's Yeast Sacchar. cerevisiae P53049 1477 166710 S1453 D T P W T L F S Q E D S I F R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 43.2 99.7 95.6 N.A. 94.2 94.7 N.A. 79.3 29.5 N.A. 71.4 N.A. 30.8 41.2 N.A. 38
Protein Similarity: 100 61.7 99.7 98.1 N.A. 96.4 97.1 N.A. 83.6 48.3 N.A. 82.8 N.A. 49.2 62.2 N.A. 54.9
P-Site Identity: 100 40 100 100 N.A. 100 100 N.A. 6.6 26.6 N.A. 60 N.A. 13.3 66.6 N.A. 20
P-Site Similarity: 100 40 100 100 N.A. 100 100 N.A. 33.3 40 N.A. 80 N.A. 20 73.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 29.5 30.4 N.A.
Protein Similarity: N.A. N.A. N.A. 45.1 50.1 N.A.
P-Site Identity: N.A. N.A. N.A. 46.6 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 15 8 8 0 0 0 8 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 72 0 0 8 8 0 0 0 0 36 15 0 0 0 0 % D
% Glu: 0 8 0 15 0 0 0 8 0 29 8 0 8 0 0 % E
% Phe: 0 0 0 0 0 0 8 0 0 8 0 0 8 79 0 % F
% Gly: 0 0 0 0 8 0 0 0 0 8 15 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 8 0 8 0 0 0 8 0 8 % I
% Lys: 0 8 8 0 8 0 0 0 8 8 0 8 0 8 0 % K
% Leu: 0 8 8 8 0 79 65 0 0 0 0 15 15 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 8 0 0 15 0 0 0 58 0 15 0 0 0 0 % N
% Pro: 0 0 79 0 0 8 0 8 0 8 8 0 0 0 0 % P
% Gln: 0 0 8 0 0 0 0 8 15 0 0 0 0 0 0 % Q
% Arg: 8 0 0 0 0 8 0 0 0 0 0 0 43 0 8 % R
% Ser: 8 22 0 65 8 0 0 72 0 8 43 72 8 0 29 % S
% Thr: 0 43 0 0 8 0 8 0 0 0 0 0 0 0 0 % T
% Val: 15 0 0 0 50 0 0 0 0 0 0 8 0 8 0 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 36 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _