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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCC5 All Species: 20.61
Human Site: S505 Identified Species: 34.87
UniProt: O15440 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15440 NP_005679.2 1437 160660 S505 A W D S S H S S I Q N S P K L
Chimpanzee Pan troglodytes XP_001163361 1366 152996 S500 K S V L H S I S F V V R K G K
Rhesus Macaque Macaca mulatta XP_001105045 1437 160671 S505 A W D S S H S S I Q N S P K L
Dog Lupus familis XP_857354 1443 161421 S505 A W D S S H S S I Q N S P K L
Cat Felis silvestris
Mouse Mus musculus Q9R1X5 1436 161112 S505 A W D S S H S S I Q N S P K L
Rat Rattus norvegicus Q9QYM0 1436 160838 S505 A W D S S H S S T Q S S P K L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505267 1266 141411 V417 A A Q A F T V V T I F N S M T
Chicken Gallus gallus Q5F364 1525 170953 A545 L K K S A Y L A A M G T F T W
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002665448 1385 153368 S503 G Q L L N D V S G E M A S S P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91660 1290 143990 I441 L S G I N L E I K P G S V V A
Honey Bee Apis mellifera XP_397384 1378 156599 S503 L E K L N E S S Q E T E Y I K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798419 1201 133943 R352 S D I M V E I R E G T F G W D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C8G9 1622 181908 R555 G G D L T P A R A F T S L S L
Baker's Yeast Sacchar. cerevisiae P53049 1477 166710 F537 L K M T H C S F E W E D Y E L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 43.2 99.7 95.6 N.A. 94.2 94.7 N.A. 79.3 29.5 N.A. 71.4 N.A. 30.8 41.2 N.A. 38
Protein Similarity: 100 61.7 99.7 98.1 N.A. 96.4 97.1 N.A. 83.6 48.3 N.A. 82.8 N.A. 49.2 62.2 N.A. 54.9
P-Site Identity: 100 6.6 100 100 N.A. 100 86.6 N.A. 6.6 6.6 N.A. 6.6 N.A. 6.6 13.3 N.A. 0
P-Site Similarity: 100 6.6 100 100 N.A. 100 93.3 N.A. 20 33.3 N.A. 26.6 N.A. 13.3 26.6 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. 29.5 30.4 N.A.
Protein Similarity: N.A. N.A. N.A. 45.1 50.1 N.A.
P-Site Identity: N.A. N.A. N.A. 20 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 43 8 0 8 8 0 8 8 15 0 0 8 0 0 8 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 43 0 0 8 0 0 0 0 0 8 0 0 8 % D
% Glu: 0 8 0 0 0 15 8 0 15 15 8 8 0 8 0 % E
% Phe: 0 0 0 0 8 0 0 8 8 8 8 8 8 0 0 % F
% Gly: 15 8 8 0 0 0 0 0 8 8 15 0 8 8 0 % G
% His: 0 0 0 0 15 36 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 8 0 0 15 8 29 8 0 0 0 8 0 % I
% Lys: 8 15 15 0 0 0 0 0 8 0 0 0 8 36 15 % K
% Leu: 29 0 8 29 0 8 8 0 0 0 0 0 8 0 50 % L
% Met: 0 0 8 8 0 0 0 0 0 8 8 0 0 8 0 % M
% Asn: 0 0 0 0 22 0 0 0 0 0 29 8 0 0 0 % N
% Pro: 0 0 0 0 0 8 0 0 0 8 0 0 36 0 8 % P
% Gln: 0 8 8 0 0 0 0 0 8 36 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 15 0 0 0 8 0 0 0 % R
% Ser: 8 15 0 43 36 8 50 58 0 0 8 50 15 15 0 % S
% Thr: 0 0 0 8 8 8 0 0 15 0 22 8 0 8 8 % T
% Val: 0 0 8 0 8 0 15 8 0 8 8 0 8 8 0 % V
% Trp: 0 36 0 0 0 0 0 0 0 8 0 0 0 8 8 % W
% Tyr: 0 0 0 0 0 8 0 0 0 0 0 0 15 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _