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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCC5
All Species:
31.21
Human Site:
S686
Identified Species:
52.82
UniProt:
O15440
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15440
NP_005679.2
1437
160660
S686
G
E
R
G
A
N
L
S
G
G
Q
R
Q
R
I
Chimpanzee
Pan troglodytes
XP_001163361
1366
152996
D676
D
E
V
I
L
L
E
D
G
E
I
C
E
K
G
Rhesus Macaque
Macaca mulatta
XP_001105045
1437
160671
S686
G
E
R
G
A
N
L
S
G
G
Q
R
Q
R
I
Dog
Lupus familis
XP_857354
1443
161421
S686
G
E
R
G
A
N
L
S
G
G
Q
R
Q
R
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1X5
1436
161112
S686
G
E
R
G
A
N
L
S
G
G
Q
R
Q
R
I
Rat
Rattus norvegicus
Q9QYM0
1436
160838
S686
G
E
R
G
A
N
L
S
G
G
Q
R
Q
R
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505267
1266
141411
T591
S
A
I
L
G
Q
M
T
L
L
E
G
S
I
A
Chicken
Gallus gallus
Q5F364
1525
170953
S766
G
E
K
G
V
N
L
S
G
G
Q
K
Q
R
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002665448
1385
153368
I678
N
H
I
F
N
N
A
I
K
K
Q
L
R
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91660
1290
143990
G615
Q
I
V
I
L
A
N
G
Q
I
K
A
L
G
D
Honey Bee
Apis mellifera
XP_397384
1378
156599
L681
V
T
H
Q
I
Q
F
L
K
H
C
D
Q
I
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798419
1201
133943
F526
T
H
V
G
R
H
I
F
T
D
C
I
M
G
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8G9
1622
181908
S741
G
E
R
G
V
N
I
S
G
G
Q
K
Q
R
V
Baker's Yeast
Sacchar. cerevisiae
P53049
1477
166710
S711
G
E
R
G
I
T
L
S
G
G
Q
K
A
R
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.2
99.7
95.6
N.A.
94.2
94.7
N.A.
79.3
29.5
N.A.
71.4
N.A.
30.8
41.2
N.A.
38
Protein Similarity:
100
61.7
99.7
98.1
N.A.
96.4
97.1
N.A.
83.6
48.3
N.A.
82.8
N.A.
49.2
62.2
N.A.
54.9
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
0
73.3
N.A.
13.3
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
20
93.3
N.A.
20
N.A.
6.6
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.5
30.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
50.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
73.3
73.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
93.3
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
36
8
8
0
0
0
0
8
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
15
8
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
8
0
8
0
8
0
0
8
% D
% Glu:
0
65
0
0
0
0
8
0
0
8
8
0
8
0
0
% E
% Phe:
0
0
0
8
0
0
8
8
0
0
0
0
0
0
0
% F
% Gly:
58
0
0
65
8
0
0
8
65
58
0
8
0
22
8
% G
% His:
0
15
8
0
0
8
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
8
15
15
15
0
15
8
0
8
8
8
0
15
43
% I
% Lys:
0
0
8
0
0
0
0
0
15
8
8
22
0
8
8
% K
% Leu:
0
0
0
8
15
8
50
8
8
8
0
8
8
0
8
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% M
% Asn:
8
0
0
0
8
58
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
8
0
15
0
0
8
0
65
0
58
0
0
% Q
% Arg:
0
0
50
0
8
0
0
0
0
0
0
36
8
58
0
% R
% Ser:
8
0
0
0
0
0
0
58
0
0
0
0
8
0
0
% S
% Thr:
8
8
0
0
0
8
0
8
8
0
0
0
0
0
8
% T
% Val:
8
0
22
0
15
0
0
0
0
0
0
0
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _