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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCC5 All Species: 30.61
Human Site: S694 Identified Species: 51.79
UniProt: O15440 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15440 NP_005679.2 1437 160660 S694 G G Q R Q R I S L A R A L Y S
Chimpanzee Pan troglodytes XP_001163361 1366 152996 T684 G E I C E K G T H K E L M E E
Rhesus Macaque Macaca mulatta XP_001105045 1437 160671 S694 G G Q R Q R I S L A R A L Y S
Dog Lupus familis XP_857354 1443 161421 S694 G G Q R Q R I S L A R A L Y S
Cat Felis silvestris
Mouse Mus musculus Q9R1X5 1436 161112 S694 G G Q R Q R I S L A R A L Y S
Rat Rattus norvegicus Q9QYM0 1436 160838 S694 G G Q R Q R I S L A R A L Y S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505267 1266 141411 V599 L L E G S I A V N G T F A Y V
Chicken Gallus gallus Q5F364 1525 170953 S774 G G Q K Q R V S L A R A V Y C
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002665448 1385 153368 T686 K K Q L R G K T V I F V T H Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91660 1290 143990 Y623 Q I K A L G D Y E S L L K T G
Honey Bee Apis mellifera XP_397384 1378 156599 V689 K H C D Q I L V M H K G R I V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798419 1201 133943 L534 T D C I M G T L R D K T Y L Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C8G9 1622 181908 S749 G G Q K Q R V S M A R A V Y S
Baker's Yeast Sacchar. cerevisiae P53049 1477 166710 N719 G G Q K A R I N L A R S V Y K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 43.2 99.7 95.6 N.A. 94.2 94.7 N.A. 79.3 29.5 N.A. 71.4 N.A. 30.8 41.2 N.A. 38
Protein Similarity: 100 61.7 99.7 98.1 N.A. 96.4 97.1 N.A. 83.6 48.3 N.A. 82.8 N.A. 49.2 62.2 N.A. 54.9
P-Site Identity: 100 6.6 100 100 N.A. 100 100 N.A. 6.6 73.3 N.A. 6.6 N.A. 0 6.6 N.A. 0
P-Site Similarity: 100 33.3 100 100 N.A. 100 100 N.A. 13.3 93.3 N.A. 33.3 N.A. 13.3 26.6 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. 29.5 30.4 N.A.
Protein Similarity: N.A. N.A. N.A. 45.1 50.1 N.A.
P-Site Identity: N.A. N.A. N.A. 73.3 60 N.A.
P-Site Similarity: N.A. N.A. N.A. 100 86.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 8 0 8 0 0 58 0 50 8 0 0 % A
% Cys: 0 0 15 8 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 8 0 8 0 0 8 0 0 8 0 0 0 0 0 % D
% Glu: 0 8 8 0 8 0 0 0 8 0 8 0 0 8 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % F
% Gly: 65 58 0 8 0 22 8 0 0 8 0 8 0 0 8 % G
% His: 0 8 0 0 0 0 0 0 8 8 0 0 0 8 0 % H
% Ile: 0 8 8 8 0 15 43 0 0 8 0 0 0 8 0 % I
% Lys: 15 8 8 22 0 8 8 0 0 8 15 0 8 0 8 % K
% Leu: 8 8 0 8 8 0 8 8 50 0 8 15 36 8 0 % L
% Met: 0 0 0 0 8 0 0 0 15 0 0 0 8 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 8 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 8 0 65 0 58 0 0 0 0 0 0 0 0 0 15 % Q
% Arg: 0 0 0 36 8 58 0 0 8 0 58 0 8 0 0 % R
% Ser: 0 0 0 0 8 0 0 50 0 8 0 8 0 0 43 % S
% Thr: 8 0 0 0 0 0 8 15 0 0 8 8 8 8 0 % T
% Val: 0 0 0 0 0 0 15 15 8 0 0 8 22 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 0 0 8 65 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _