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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCC5 All Species: 9.09
Human Site: S816 Identified Species: 15.38
UniProt: O15440 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15440 NP_005679.2 1437 160660 S816 D K G P K T G S V K K E K A V
Chimpanzee Pan troglodytes XP_001163361 1366 152996 A805 L F L P L P C A H V C S P X X
Rhesus Macaque Macaca mulatta XP_001105045 1437 160671 S816 D K G P K T G S V K K E K A V
Dog Lupus familis XP_857354 1443 161421 S816 D K G P K T G S V K K E K A V
Cat Felis silvestris
Mouse Mus musculus Q9R1X5 1436 161112 V816 K G P K P G S V K K E K A V K
Rat Rattus norvegicus Q9QYM0 1436 160838 V816 K G P K P G S V K K E K A V K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505267 1266 141411 H720 K T V L F V T H Q L Q Y L V D
Chicken Gallus gallus Q5F364 1525 170953 A898 N G V L V N D A T G K L M H R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002665448 1385 153368 L808 L G G W P V F L F I L A L F I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91660 1290 143990 H744 K E S T A A G H G E M E D M E
Honey Bee Apis mellifera XP_397384 1378 156599 L810 L V F L T L F L S I G S S A F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798419 1201 133943 L655 V E S M G G Y L N A T G L F L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C8G9 1622 181908 Q871 N G N A N N L Q K D G I E T K
Baker's Yeast Sacchar. cerevisiae P53049 1477 166710 A847 L T E L K K K A T E M S Q T A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 43.2 99.7 95.6 N.A. 94.2 94.7 N.A. 79.3 29.5 N.A. 71.4 N.A. 30.8 41.2 N.A. 38
Protein Similarity: 100 61.7 99.7 98.1 N.A. 96.4 97.1 N.A. 83.6 48.3 N.A. 82.8 N.A. 49.2 62.2 N.A. 54.9
P-Site Identity: 100 6.6 100 100 N.A. 6.6 6.6 N.A. 0 6.6 N.A. 6.6 N.A. 13.3 6.6 N.A. 0
P-Site Similarity: 100 13.3 100 100 N.A. 20 20 N.A. 6.6 20 N.A. 13.3 N.A. 26.6 6.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 29.5 30.4 N.A.
Protein Similarity: N.A. N.A. N.A. 45.1 50.1 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 8 8 0 22 0 8 0 8 15 29 8 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 8 0 0 0 0 % C
% Asp: 22 0 0 0 0 0 8 0 0 8 0 0 8 0 8 % D
% Glu: 0 15 8 0 0 0 0 0 0 15 15 29 8 0 8 % E
% Phe: 0 8 8 0 8 0 15 0 8 0 0 0 0 15 8 % F
% Gly: 0 36 29 0 8 22 29 0 8 8 15 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 15 8 0 0 0 0 8 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 15 0 8 0 0 8 % I
% Lys: 29 22 0 15 29 8 8 0 22 36 29 15 22 0 22 % K
% Leu: 29 0 8 29 8 8 8 22 0 8 8 8 22 0 8 % L
% Met: 0 0 0 8 0 0 0 0 0 0 15 0 8 8 0 % M
% Asn: 15 0 8 0 8 15 0 0 8 0 0 0 0 0 0 % N
% Pro: 0 0 15 29 22 8 0 0 0 0 0 0 8 0 0 % P
% Gln: 0 0 0 0 0 0 0 8 8 0 8 0 8 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % R
% Ser: 0 0 15 0 0 0 15 22 8 0 0 22 8 0 0 % S
% Thr: 0 15 0 8 8 22 8 0 15 0 8 0 0 15 0 % T
% Val: 8 8 15 0 8 15 0 15 22 8 0 0 0 22 22 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _