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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCC5
All Species:
21.21
Human Site:
T496
Identified Species:
35.9
UniProt:
O15440
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15440
NP_005679.2
1437
160660
T496
K
I
E
M
K
N
A
T
L
A
W
D
S
S
H
Chimpanzee
Pan troglodytes
XP_001163361
1366
152996
S491
G
P
E
E
Q
S
D
S
L
K
S
V
L
H
S
Rhesus Macaque
Macaca mulatta
XP_001105045
1437
160671
T496
K
I
E
M
K
N
A
T
L
A
W
D
S
S
H
Dog
Lupus familis
XP_857354
1443
161421
T496
K
I
E
V
K
N
A
T
L
A
W
D
S
S
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1X5
1436
161112
T496
K
I
E
M
K
N
A
T
L
A
W
D
S
S
H
Rat
Rattus norvegicus
Q9QYM0
1436
160838
T496
K
I
E
M
K
N
A
T
L
A
W
D
S
S
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505267
1266
141411
L408
H
M
I
L
G
Y
D
L
T
A
A
Q
A
F
T
Chicken
Gallus gallus
Q5F364
1525
170953
K536
E
I
R
Q
K
E
L
K
V
L
K
K
S
A
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002665448
1385
153368
T494
H
A
I
L
E
E
E
T
H
G
Q
L
L
N
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91660
1290
143990
Y432
W
D
P
N
S
P
D
Y
T
L
S
G
I
N
L
Honey Bee
Apis mellifera
XP_397384
1378
156599
V494
V
S
Y
L
R
N
K
V
E
L
E
K
L
N
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798419
1201
133943
D343
E
P
N
P
R
L
E
D
T
S
D
I
M
V
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8G9
1622
181908
L546
V
S
F
G
V
F
S
L
L
G
G
D
L
T
P
Baker's Yeast
Sacchar. cerevisiae
P53049
1477
166710
L528
S
P
G
F
D
P
K
L
A
L
K
M
T
H
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.2
99.7
95.6
N.A.
94.2
94.7
N.A.
79.3
29.5
N.A.
71.4
N.A.
30.8
41.2
N.A.
38
Protein Similarity:
100
61.7
99.7
98.1
N.A.
96.4
97.1
N.A.
83.6
48.3
N.A.
82.8
N.A.
49.2
62.2
N.A.
54.9
P-Site Identity:
100
13.3
100
93.3
N.A.
100
100
N.A.
6.6
20
N.A.
6.6
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
33.3
100
100
N.A.
100
100
N.A.
26.6
46.6
N.A.
26.6
N.A.
6.6
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.5
30.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
50.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
36
0
8
43
8
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
8
0
0
8
0
22
8
0
0
8
43
0
0
8
% D
% Glu:
15
0
43
8
8
15
15
0
8
0
8
0
0
0
15
% E
% Phe:
0
0
8
8
0
8
0
0
0
0
0
0
0
8
0
% F
% Gly:
8
0
8
8
8
0
0
0
0
15
8
8
0
0
0
% G
% His:
15
0
0
0
0
0
0
0
8
0
0
0
0
15
36
% H
% Ile:
0
43
15
0
0
0
0
0
0
0
0
8
8
0
0
% I
% Lys:
36
0
0
0
43
0
15
8
0
8
15
15
0
0
0
% K
% Leu:
0
0
0
22
0
8
8
22
50
29
0
8
29
0
8
% L
% Met:
0
8
0
29
0
0
0
0
0
0
0
8
8
0
0
% M
% Asn:
0
0
8
8
0
43
0
0
0
0
0
0
0
22
0
% N
% Pro:
0
22
8
8
0
15
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
0
8
8
0
0
0
0
0
8
8
0
0
0
% Q
% Arg:
0
0
8
0
15
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
15
0
0
8
8
8
8
0
8
15
0
43
36
8
% S
% Thr:
0
0
0
0
0
0
0
43
22
0
0
0
8
8
8
% T
% Val:
15
0
0
8
8
0
0
8
8
0
0
8
0
8
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
36
0
0
0
0
% W
% Tyr:
0
0
8
0
0
8
0
8
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _