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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCC5
All Species:
24.24
Human Site:
T577
Identified Species:
41.03
UniProt:
O15440
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15440
NP_005679.2
1437
160660
T577
G
H
L
R
L
Q
R
T
L
H
S
I
D
L
E
Chimpanzee
Pan troglodytes
XP_001163361
1366
152996
Y567
N
I
L
F
G
E
K
Y
D
H
Q
R
Y
S
H
Rhesus Macaque
Macaca mulatta
XP_001105045
1437
160671
T577
G
H
L
R
L
Q
R
T
L
H
S
I
D
L
E
Dog
Lupus familis
XP_857354
1443
161421
T577
G
N
L
R
L
Q
R
T
L
Y
N
I
D
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1X5
1436
161112
T577
G
S
L
R
L
Q
R
T
L
Y
N
I
D
L
E
Rat
Rattus norvegicus
Q9QYM0
1436
160838
T577
G
S
M
R
L
Q
R
T
L
Y
N
I
D
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505267
1266
141411
H483
T
L
A
W
D
F
S
H
S
S
I
E
S
S
P
Chicken
Gallus gallus
Q5F364
1525
170953
S657
W
S
K
T
D
P
P
S
L
N
S
I
N
F
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002665448
1385
153368
A570
T
L
L
E
G
T
V
A
V
D
G
D
F
A
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91660
1290
143990
S507
L
F
G
Q
P
M
D
S
Q
R
Y
E
E
V
V
Honey Bee
Apis mellifera
XP_397384
1378
156599
F573
A
W
I
V
N
A
T
F
K
E
N
I
L
F
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798419
1201
133943
E418
L
G
Q
M
H
T
L
E
G
V
C
Q
V
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8G9
1622
181908
T631
D
S
K
A
D
R
P
T
L
S
N
I
N
L
D
Baker's Yeast
Sacchar. cerevisiae
P53049
1477
166710
G603
L
E
K
T
S
F
R
G
F
K
D
L
N
F
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.2
99.7
95.6
N.A.
94.2
94.7
N.A.
79.3
29.5
N.A.
71.4
N.A.
30.8
41.2
N.A.
38
Protein Similarity:
100
61.7
99.7
98.1
N.A.
96.4
97.1
N.A.
83.6
48.3
N.A.
82.8
N.A.
49.2
62.2
N.A.
54.9
P-Site Identity:
100
13.3
100
80
N.A.
80
73.3
N.A.
0
20
N.A.
6.6
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
26.6
100
100
N.A.
93.3
93.3
N.A.
0
40
N.A.
13.3
N.A.
26.6
20
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.5
30.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
50.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
0
8
0
8
0
0
0
0
0
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
8
0
0
0
22
0
8
0
8
8
8
8
36
0
15
% D
% Glu:
0
8
0
8
0
8
0
8
0
8
0
15
8
0
36
% E
% Phe:
0
8
0
8
0
15
0
8
8
0
0
0
8
22
0
% F
% Gly:
36
8
8
0
15
0
0
8
8
0
8
0
0
0
15
% G
% His:
0
15
0
0
8
0
0
8
0
22
0
0
0
0
8
% H
% Ile:
0
8
8
0
0
0
0
0
0
0
8
58
0
0
0
% I
% Lys:
0
0
22
0
0
0
8
0
8
8
0
0
0
0
0
% K
% Leu:
22
15
43
0
36
0
8
0
50
0
0
8
8
43
0
% L
% Met:
0
0
8
8
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
0
8
0
0
0
0
8
36
0
22
0
0
% N
% Pro:
0
0
0
0
8
8
15
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
8
8
0
36
0
0
8
0
8
8
0
0
0
% Q
% Arg:
0
0
0
36
0
8
43
0
0
8
0
8
0
0
0
% R
% Ser:
0
29
0
0
8
0
8
15
8
15
22
0
8
15
0
% S
% Thr:
15
0
0
15
0
15
8
43
0
0
0
0
0
0
8
% T
% Val:
0
0
0
8
0
0
8
0
8
8
0
0
8
8
8
% V
% Trp:
8
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
22
8
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _