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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCC5
All Species:
23.64
Human Site:
Y1423
Identified Species:
40
UniProt:
O15440
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15440
NP_005679.2
1437
160660
Y1423
S
N
D
S
S
R
F
Y
A
M
F
A
A
A
E
Chimpanzee
Pan troglodytes
XP_001163361
1366
152996
A1357
E
K
P
D
S
A
F
A
M
L
L
A
A
E
V
Rhesus Macaque
Macaca mulatta
XP_001105045
1437
160671
Y1423
S
N
D
S
S
R
F
Y
A
M
F
A
A
A
E
Dog
Lupus familis
XP_857354
1443
161421
Y1429
S
N
D
S
S
R
F
Y
A
M
F
A
A
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1X5
1436
161112
Y1422
S
N
D
S
S
R
F
Y
A
M
F
A
A
A
E
Rat
Rattus norvegicus
Q9QYM0
1436
160838
Y1422
S
N
D
S
S
R
F
Y
A
M
C
A
A
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505267
1266
141411
S1259
P
Q
E
P
V
L
F
S
G
T
V
R
S
H
L
Chicken
Gallus gallus
Q5F364
1525
170953
S1517
Q
A
K
G
L
F
Y
S
M
A
K
D
S
G
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002665448
1385
153368
C1371
A
N
E
N
S
R
F
C
A
M
L
A
A
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91660
1290
143990
I1283
S
Y
E
G
L
L
K
I
A
Q
E
V
R
F
N
Honey Bee
Apis mellifera
XP_397384
1378
156599
S1365
S
N
S
N
S
E
F
S
K
M
M
I
S
A
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798419
1201
133943
L1194
S
I
F
S
K
M
V
L
P
A
E
S
Q
N
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8G9
1622
181908
S1467
S
N
G
E
S
S
F
S
K
M
V
Q
S
T
G
Baker's Yeast
Sacchar. cerevisiae
P53049
1477
166710
R1460
S
Q
E
D
S
I
F
R
S
M
C
S
R
S
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.2
99.7
95.6
N.A.
94.2
94.7
N.A.
79.3
29.5
N.A.
71.4
N.A.
30.8
41.2
N.A.
38
Protein Similarity:
100
61.7
99.7
98.1
N.A.
96.4
97.1
N.A.
83.6
48.3
N.A.
82.8
N.A.
49.2
62.2
N.A.
54.9
P-Site Identity:
100
26.6
100
93.3
N.A.
100
93.3
N.A.
6.6
0
N.A.
60
N.A.
13.3
46.6
N.A.
20
P-Site Similarity:
100
33.3
100
93.3
N.A.
100
93.3
N.A.
20
13.3
N.A.
80
N.A.
20
60
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.5
30.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
50.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
8
0
8
50
15
0
50
50
36
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
15
0
0
0
0
% C
% Asp:
0
0
36
15
0
0
0
0
0
0
0
8
0
0
0
% D
% Glu:
8
0
29
8
0
8
0
0
0
0
15
0
0
8
58
% E
% Phe:
0
0
8
0
0
8
79
0
0
0
29
0
0
8
0
% F
% Gly:
0
0
8
15
0
0
0
0
8
0
0
0
0
8
15
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
8
0
0
0
8
0
8
0
0
0
8
0
0
0
% I
% Lys:
0
8
8
0
8
0
8
0
15
0
8
0
0
0
0
% K
% Leu:
0
0
0
0
15
15
0
8
0
8
15
0
0
0
15
% L
% Met:
0
0
0
0
0
8
0
0
15
65
8
0
0
0
0
% M
% Asn:
0
58
0
15
0
0
0
0
0
0
0
0
0
8
8
% N
% Pro:
8
0
8
8
0
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
8
15
0
0
0
0
0
0
0
8
0
8
8
0
0
% Q
% Arg:
0
0
0
0
0
43
0
8
0
0
0
8
15
0
0
% R
% Ser:
72
0
8
43
72
8
0
29
8
0
0
15
29
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% T
% Val:
0
0
0
0
8
0
8
0
0
0
15
8
0
15
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
8
36
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _