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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCC5 All Species: 16.67
Human Site: Y342 Identified Species: 28.21
UniProt: O15440 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15440 NP_005679.2 1437 160660 Y342 F A S R L T A Y F R R K C V A
Chimpanzee Pan troglodytes XP_001163361 1366 152996 R333 Q D I R R R E R K L L E K A G
Rhesus Macaque Macaca mulatta XP_001105045 1437 160671 Y342 F A S R L T A Y F R R K C V A
Dog Lupus familis XP_857354 1443 161421 Y342 F V S R I T A Y F R R K C V T
Cat Felis silvestris
Mouse Mus musculus Q9R1X5 1436 161112 Y342 F V S R L T A Y F R R K R V A
Rat Rattus norvegicus Q9QYM0 1436 160838 Y342 F V S R L T A Y F R R K C V A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505267 1266 141411 I257 E K S L G E L I N V C S N D G
Chicken Gallus gallus Q5F364 1525 170953 H381 C L Q T L I L H Q Y F H I C F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002665448 1385 153368 G336 Q K G L S Q G G I R D E E R Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91660 1290 143990 E281 V L K M Y A W E Q P F E Q M V
Honey Bee Apis mellifera XP_397384 1378 156599 C343 L M N E I L E C I K L I K M Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798419 1201 133943 Q192 F S L F F P L Q M I L G R A V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C8G9 1622 181908 L371 V M R V G Y R L R S A L I A A
Baker's Yeast Sacchar. cerevisiae P53049 1477 166710 G375 F A F K L I L G F R I A A N I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 43.2 99.7 95.6 N.A. 94.2 94.7 N.A. 79.3 29.5 N.A. 71.4 N.A. 30.8 41.2 N.A. 38
Protein Similarity: 100 61.7 99.7 98.1 N.A. 96.4 97.1 N.A. 83.6 48.3 N.A. 82.8 N.A. 49.2 62.2 N.A. 54.9
P-Site Identity: 100 6.6 100 80 N.A. 86.6 93.3 N.A. 6.6 6.6 N.A. 6.6 N.A. 0 0 N.A. 6.6
P-Site Similarity: 100 13.3 100 86.6 N.A. 86.6 93.3 N.A. 6.6 13.3 N.A. 13.3 N.A. 13.3 26.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 29.5 30.4 N.A.
Protein Similarity: N.A. N.A. N.A. 45.1 50.1 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 22 0 0 0 8 36 0 0 0 8 8 8 22 36 % A
% Cys: 8 0 0 0 0 0 0 8 0 0 8 0 29 8 0 % C
% Asp: 0 8 0 0 0 0 0 0 0 0 8 0 0 8 0 % D
% Glu: 8 0 0 8 0 8 15 8 0 0 0 22 8 0 0 % E
% Phe: 50 0 8 8 8 0 0 0 43 0 15 0 0 0 8 % F
% Gly: 0 0 8 0 15 0 8 15 0 0 0 8 0 0 15 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 8 0 0 0 % H
% Ile: 0 0 8 0 15 15 0 8 15 8 8 8 15 0 8 % I
% Lys: 0 15 8 8 0 0 0 0 8 8 0 36 15 0 0 % K
% Leu: 8 15 8 15 43 8 29 8 0 8 22 8 0 0 0 % L
% Met: 0 15 0 8 0 0 0 0 8 0 0 0 0 15 0 % M
% Asn: 0 0 8 0 0 0 0 0 8 0 0 0 8 8 0 % N
% Pro: 0 0 0 0 0 8 0 0 0 8 0 0 0 0 0 % P
% Gln: 15 0 8 0 0 8 0 8 15 0 0 0 8 0 8 % Q
% Arg: 0 0 8 43 8 8 8 8 8 50 36 0 15 8 0 % R
% Ser: 0 8 43 0 8 0 0 0 0 8 0 8 0 0 0 % S
% Thr: 0 0 0 8 0 36 0 0 0 0 0 0 0 0 8 % T
% Val: 15 22 0 8 0 0 0 0 0 8 0 0 0 36 15 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 8 0 36 0 8 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _