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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CD3EAP
All Species:
8.79
Human Site:
T249
Identified Species:
38.67
UniProt:
O15446
Number Species:
5
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15446
NP_036231.1
510
54986
T249
L
G
V
L
F
P
S
T
T
K
K
R
K
K
P
Chimpanzee
Pan troglodytes
XP_001164858
510
54940
T249
L
G
V
L
F
P
S
T
T
K
K
R
K
K
P
Rhesus Macaque
Macaca mulatta
XP_001110546
515
55824
T252
L
G
V
L
L
P
S
T
T
K
K
R
K
K
P
Dog
Lupus familis
XP_855118
530
57442
K257
K
K
R
K
K
K
P
K
E
A
E
M
V
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q76KJ5
399
43064
L168
G
P
G
S
A
S
A
L
R
S
P
T
S
G
K
Rat
Rattus norvegicus
NP_001102886
458
49394
A226
H
V
D
E
E
A
E
A
K
G
M
E
P
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
89.9
57.5
N.A.
48.8
51.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
92.2
66.4
N.A.
55.8
59.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
6.6
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
20
N.A.
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
17
17
17
17
0
17
0
0
0
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
17
17
0
17
0
17
0
17
17
0
17
0
% E
% Phe:
0
0
0
0
34
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
17
50
17
0
0
0
0
0
0
17
0
0
0
17
0
% G
% His:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
17
17
0
17
17
17
0
17
17
50
50
0
50
50
17
% K
% Leu:
50
0
0
50
17
0
0
17
0
0
0
0
0
17
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
17
17
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
17
0
0
0
50
17
0
0
0
17
0
17
0
67
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
17
0
0
0
0
0
17
0
0
50
0
0
0
% R
% Ser:
0
0
0
17
0
17
50
0
0
17
0
0
17
0
0
% S
% Thr:
0
0
0
0
0
0
0
50
50
0
0
17
0
0
0
% T
% Val:
0
17
50
0
0
0
0
0
0
0
0
0
17
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _