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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CAPN5 All Species: 17.27
Human Site: S621 Identified Species: 34.55
UniProt: O15484 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15484 NP_004046.2 640 73169 S621 D R N S R Q P S N L P G T V A
Chimpanzee Pan troglodytes XP_001146965 641 74541 K622 K K G G P T A K V K Q G H I S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_542293 640 73142 S621 D R S G R Q P S D L P G T V T
Cat Felis silvestris
Mouse Mus musculus O08688 640 72936 S621 D R S S R Q P S D L P G I V A
Rat Rattus norvegicus Q8R4C0 640 73046 S621 D R S G R Q P S D L P G I V A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518356 408 46381 S389 D R S S K P A S E R P G T V T
Chicken Gallus gallus Q92177 810 93542 F703 D G S G K I N F D E F R H L W
Frog Xenopus laevis NP_001080808 642 73235 G623 N K G N K K S G E I S G T I N
Zebra Danio Brachydanio rerio XP_001345114 642 73723 N623 D K G S R Q D N N L P G T L T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q11002 828 93944 F721 D K S G K L G F E E F E T L L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22036 648 73596 T625 R D T T L Q L T D P R G T V I
Sea Urchin Strong. purpuratus XP_792213 642 72430 E622 K K R G R D S E D A A G G Q V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 46.4 N.A. 92 N.A. 92.1 90.6 N.A. 51.4 30.8 73.9 71.6 N.A. 30.7 N.A. 40.1 47.6
Protein Similarity: 100 65.5 N.A. 95.6 N.A. 96 94.8 N.A. 57.3 46.9 86.2 83.8 N.A. 45.2 N.A. 57.2 64.9
P-Site Identity: 100 6.6 N.A. 73.3 N.A. 80 73.3 N.A. 53.3 6.6 13.3 60 N.A. 13.3 N.A. 26.6 13.3
P-Site Similarity: 100 26.6 N.A. 86.6 N.A. 93.3 86.6 N.A. 66.6 33.3 60 80 N.A. 40 N.A. 46.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 17 0 0 9 9 0 0 0 25 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 67 9 0 0 0 9 9 0 50 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 9 25 17 0 9 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 17 0 0 17 0 0 0 0 % F
% Gly: 0 9 25 50 0 0 9 9 0 0 0 84 9 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % H
% Ile: 0 0 0 0 0 9 0 0 0 9 0 0 17 17 9 % I
% Lys: 17 42 0 0 34 9 0 9 0 9 0 0 0 0 0 % K
% Leu: 0 0 0 0 9 9 9 0 0 42 0 0 0 25 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 9 9 0 0 9 9 17 0 0 0 0 0 9 % N
% Pro: 0 0 0 0 9 9 34 0 0 9 50 0 0 0 0 % P
% Gln: 0 0 0 0 0 50 0 0 0 0 9 0 0 9 0 % Q
% Arg: 9 42 9 0 50 0 0 0 0 9 9 9 0 0 0 % R
% Ser: 0 0 50 34 0 0 17 42 0 0 9 0 0 0 9 % S
% Thr: 0 0 9 9 0 9 0 9 0 0 0 0 59 0 25 % T
% Val: 0 0 0 0 0 0 0 0 9 0 0 0 0 50 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _