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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GYG2
All Species:
7.27
Human Site:
S399
Identified Species:
16
UniProt:
O15488
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15488
NP_001073324.1
501
55184
S399
C
D
P
L
S
Q
P
S
P
Q
P
A
D
F
T
Chimpanzee
Pan troglodytes
XP_520910
542
59417
S440
C
D
P
L
S
Q
P
S
P
Q
P
A
D
F
T
Rhesus Macaque
Macaca mulatta
XP_001116112
641
68641
Y508
G
T
E
R
A
S
S
Y
I
L
G
T
T
R
R
Dog
Lupus familis
XP_548837
492
54244
T399
Q
C
A
D
S
S
G
T
Q
S
T
S
Q
P
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9R062
333
37384
H242
S
Q
D
P
T
V
S
H
P
E
F
L
N
L
W
Rat
Rattus norvegicus
O08730
333
37360
H242
S
Q
D
P
I
V
S
H
P
E
F
L
N
L
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507071
361
40969
A270
S
I
A
E
D
N
R
A
R
G
G
E
H
Q
N
Chicken
Gallus gallus
XP_416857
416
46887
K325
S
S
E
E
L
T
F
K
A
Q
P
V
Y
E
T
Frog
Xenopus laevis
NP_001104212
362
41228
G271
T
D
Q
E
E
T
E
G
A
N
S
Q
Q
H
Q
Zebra Danio
Brachydanio rerio
NP_001002062
321
36011
R230
Y
T
Y
N
P
S
Q
R
R
L
K
G
D
M
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624798
636
71859
S403
Q
N
D
I
F
I
D
S
P
A
T
N
F
S
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.4
58.6
71.2
N.A.
43.5
43.5
N.A.
49.9
51.2
48
41.9
N.A.
N.A.
34.1
N.A.
N.A.
Protein Similarity:
100
83
63.4
78.4
N.A.
52.6
52.6
N.A.
57.6
62
59
51.7
N.A.
N.A.
46.7
N.A.
N.A.
P-Site Identity:
100
100
0
13.3
N.A.
6.6
6.6
N.A.
0
20
6.6
6.6
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
100
100
6.6
26.6
N.A.
26.6
20
N.A.
6.6
20
6.6
6.6
N.A.
N.A.
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
0
10
0
0
10
19
10
0
19
0
0
0
% A
% Cys:
19
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
28
28
10
10
0
10
0
0
0
0
0
28
0
0
% D
% Glu:
0
0
19
28
10
0
10
0
0
19
0
10
0
10
0
% E
% Phe:
0
0
0
0
10
0
10
0
0
0
19
0
10
19
0
% F
% Gly:
10
0
0
0
0
0
10
10
0
10
19
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
19
0
0
0
0
10
10
0
% H
% Ile:
0
10
0
10
10
10
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% K
% Leu:
0
0
0
19
10
0
0
0
0
19
0
19
0
19
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
10
0
10
0
10
0
0
0
10
0
10
19
0
10
% N
% Pro:
0
0
19
19
10
0
19
0
46
0
28
0
0
10
0
% P
% Gln:
19
19
10
0
0
19
10
0
10
28
0
10
19
10
19
% Q
% Arg:
0
0
0
10
0
0
10
10
19
0
0
0
0
10
10
% R
% Ser:
37
10
0
0
28
28
28
28
0
10
10
10
0
10
0
% S
% Thr:
10
19
0
0
10
19
0
10
0
0
19
10
10
0
37
% T
% Val:
0
0
0
0
0
19
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
19
% W
% Tyr:
10
0
10
0
0
0
0
10
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _