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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RGS16
All Species:
25.45
Human Site:
S174
Identified Species:
56
UniProt:
O15492
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15492
NP_002919.3
202
22768
S174
S
Y
P
R
F
L
K
S
P
A
Y
R
D
L
A
Chimpanzee
Pan troglodytes
XP_001161520
201
22563
S173
S
Y
P
R
F
L
K
S
P
A
Y
R
D
L
A
Rhesus Macaque
Macaca mulatta
XP_001114540
202
22746
S174
S
Y
P
R
F
L
K
S
P
A
Y
R
D
L
A
Dog
Lupus familis
XP_547431
327
37363
S299
S
Y
P
R
F
L
K
S
P
A
Y
R
D
L
A
Cat
Felis silvestris
Mouse
Mus musculus
P97428
201
22673
S173
S
Y
P
R
F
L
K
S
P
A
Y
R
D
L
A
Rat
Rattus norvegicus
P56700
199
22382
L171
K
D
S
Y
P
R
F
L
K
S
P
A
Y
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516363
203
22952
S173
S
Y
P
R
F
L
R
S
A
A
Y
R
D
L
A
Chicken
Gallus gallus
Q7SZC6
208
23504
S171
S
Y
R
R
F
L
K
S
P
Y
L
D
L
V
S
Frog
Xenopus laevis
A1A643
201
23280
E174
K
M
I
F
I
L
M
E
R
D
S
Y
P
R
F
Zebra Danio
Brachydanio rerio
Q6DGI0
174
20503
D147
V
Y
S
L
M
E
K
D
S
Y
P
R
F
I
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P49808
169
19576
Q142
N
Q
I
Y
T
L
M
Q
R
D
S
Y
P
R
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
95.5
48
N.A.
85.1
84.1
N.A.
72.9
47.1
34.1
41
N.A.
N.A.
N.A.
33.6
N.A.
Protein Similarity:
100
99
97
53.2
N.A.
89.1
88.1
N.A.
81.7
62.9
50.5
56.9
N.A.
N.A.
N.A.
51.4
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
86.6
53.3
6.6
20
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
6.6
N.A.
93.3
66.6
6.6
26.6
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
55
0
10
0
0
55
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
10
0
19
0
10
55
0
10
% D
% Glu:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
10
64
0
10
0
0
0
0
0
10
0
19
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
19
0
10
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
19
0
0
0
0
0
64
0
10
0
0
0
0
0
0
% K
% Leu:
0
0
0
10
0
82
0
10
0
0
10
0
10
55
0
% L
% Met:
0
10
0
0
10
0
19
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
55
0
10
0
0
0
55
0
19
0
19
0
0
% P
% Gln:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
64
0
10
10
0
19
0
0
64
0
28
10
% R
% Ser:
64
0
19
0
0
0
0
64
10
10
19
0
0
0
10
% S
% Thr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% T
% Val:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
73
0
19
0
0
0
0
0
19
55
19
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _