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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YKT6
All Species:
38.48
Human Site:
S174
Identified Species:
56.44
UniProt:
O15498
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15498
NP_006546.1
198
22418
S174
L
D
D
L
V
S
K
S
E
V
L
G
T
Q
S
Chimpanzee
Pan troglodytes
XP_001143818
250
27829
L174
F
L
M
A
T
A
C
L
T
I
Y
W
V
P
R
Rhesus Macaque
Macaca mulatta
XP_001092856
326
36094
S175
L
G
G
L
V
S
K
S
E
V
L
G
T
G
A
Dog
Lupus familis
XP_532720
169
19159
E146
D
D
L
V
S
K
S
E
V
L
G
T
Q
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQW1
198
22296
S174
L
D
D
L
V
S
K
S
E
V
L
G
T
Q
S
Rat
Rattus norvegicus
Q5EGY4
198
22351
S174
L
D
D
L
V
S
K
S
E
V
L
G
T
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521372
163
18456
E140
D
D
L
V
S
K
S
E
V
L
G
T
Q
S
K
Chicken
Gallus gallus
NP_001107216
198
22405
S174
L
D
D
L
V
S
K
S
E
V
L
G
V
Q
S
Frog
Xenopus laevis
Q32N70
198
22594
S174
L
D
D
L
V
S
K
S
E
V
L
G
T
Q
S
Zebra Danio
Brachydanio rerio
Q7ZUN8
198
22387
S174
L
D
D
L
V
Q
K
S
E
H
L
G
N
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572423
199
22400
S175
L
D
D
M
V
S
K
S
E
K
L
S
L
Q
S
Honey Bee
Apis mellifera
XP_624934
200
22741
S175
L
D
D
L
V
S
K
S
Q
G
L
S
V
Q
S
Nematode Worm
Caenorhab. elegans
NP_498605
201
23132
K176
K
L
D
D
L
V
K
K
S
E
N
L
S
D
Q
Sea Urchin
Strong. purpuratus
XP_779975
205
23371
S174
L
D
D
L
V
A
K
S
D
D
L
S
A
Q
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZRD6
199
22525
S175
L
D
S
L
V
E
K
S
S
D
L
S
M
A
S
Baker's Yeast
Sacchar. cerevisiae
P36015
200
22688
D174
E
K
L
D
N
L
V
D
K
S
E
S
L
T
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
66
50.9
80.8
N.A.
92.9
94.9
N.A.
75.2
86.3
88.8
84.8
N.A.
61.3
58.5
55.7
57
Protein Similarity:
100
69.1
54.9
84.3
N.A.
96.4
97.9
N.A.
77.2
92.9
94.4
90.4
N.A.
77.3
75.5
72.1
74.6
P-Site Identity:
100
0
73.3
6.6
N.A.
100
100
N.A.
6.6
93.3
100
80
N.A.
73.3
73.3
13.3
66.6
P-Site Similarity:
100
13.3
80
20
N.A.
100
100
N.A.
20
93.3
100
80
N.A.
80
80
26.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.2
47.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
61.8
67
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
13
0
0
0
0
0
0
7
7
13
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
13
75
63
13
0
0
0
7
7
13
0
0
0
7
0
% D
% Glu:
7
0
0
0
0
7
0
13
50
7
7
0
0
0
0
% E
% Phe:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
7
0
0
0
0
0
0
7
13
44
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% I
% Lys:
7
7
0
0
0
13
75
7
7
7
0
0
0
0
13
% K
% Leu:
69
13
19
63
7
7
0
7
0
13
69
7
13
0
0
% L
% Met:
0
0
7
7
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
0
7
0
0
0
0
0
7
0
7
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% P
% Gln:
0
0
0
0
0
7
0
0
7
0
0
0
13
57
7
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% R
% Ser:
0
0
7
0
13
50
13
69
13
7
0
32
7
13
63
% S
% Thr:
0
0
0
0
7
0
0
0
7
0
0
13
32
7
0
% T
% Val:
0
0
0
13
69
7
7
0
13
38
0
0
19
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _