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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INSIG1
All Species:
4.24
Human Site:
S16
Identified Species:
9.33
UniProt:
O15503
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15503
NP_005533.2
277
29987
S16
W
S
C
S
C
A
H
S
A
R
R
R
G
P
P
Chimpanzee
Pan troglodytes
XP_001145487
277
30007
S16
W
S
C
S
R
A
H
S
A
R
R
R
G
P
P
Rhesus Macaque
Macaca mulatta
XP_001111307
284
31535
A34
P
A
R
S
R
P
V
A
S
G
S
G
A
G
H
Dog
Lupus familis
XP_850396
273
28967
G16
W
S
C
S
C
A
Q
G
A
R
H
R
G
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGI3
259
28194
W9
P
R
L
H
D
H
V
W
N
Y
P
S
A
G
A
Rat
Rattus norvegicus
Q08755
259
28213
W9
P
R
L
H
D
H
V
W
S
Y
P
S
A
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512717
273
29878
R16
W
N
C
S
C
T
T
R
E
R
H
K
S
H
L
Chicken
Gallus gallus
Q5ZMT9
252
27336
Frog
Xenopus laevis
Q6DF80
251
27551
Zebra Danio
Brachydanio rerio
Q8AV61
251
27578
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001201451
248
27492
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
58.7
84.1
N.A.
79.4
80.1
N.A.
81.9
77.6
75
70.4
N.A.
N.A.
N.A.
N.A.
54.8
Protein Similarity:
100
99.6
61.9
87
N.A.
83.3
84.1
N.A.
86.6
80.8
80.5
79.7
N.A.
N.A.
N.A.
N.A.
66
P-Site Identity:
100
93.3
6.6
73.3
N.A.
0
0
N.A.
33.3
0
0
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
93.3
26.6
73.3
N.A.
0
6.6
N.A.
46.6
0
0
0
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
28
0
10
28
0
0
0
28
0
19
% A
% Cys:
0
0
37
0
28
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
19
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
10
0
10
28
28
0
% G
% His:
0
0
0
19
0
19
19
0
0
0
19
0
0
10
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% K
% Leu:
0
0
19
0
0
0
0
0
0
0
0
0
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
28
0
0
0
0
10
0
0
0
0
19
0
0
19
28
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
19
10
0
19
0
0
10
0
37
19
28
0
0
0
% R
% Ser:
0
28
0
46
0
0
0
19
19
0
10
19
10
0
0
% S
% Thr:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
28
0
0
0
0
0
0
0
0
% V
% Trp:
37
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
19
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _