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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INSIG1
All Species:
5.76
Human Site:
S74
Identified Species:
12.67
UniProt:
O15503
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15503
NP_005533.2
277
29987
S74
M
S
G
P
E
P
G
S
P
Y
P
N
T
W
H
Chimpanzee
Pan troglodytes
XP_001145487
277
30007
S74
M
S
G
P
E
P
G
S
P
Y
P
N
T
W
H
Rhesus Macaque
Macaca mulatta
XP_001111307
284
31535
S89
L
A
A
G
P
S
R
S
G
P
P
V
V
G
L
Dog
Lupus familis
XP_850396
273
28967
G71
G
A
R
G
A
G
G
G
S
P
G
S
W
H
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGI3
259
28194
H64
A
R
P
G
S
W
H
H
D
L
V
Q
R
S
L
Rat
Rattus norvegicus
Q08755
259
28213
H64
A
R
P
G
S
W
H
H
D
L
V
Q
R
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512717
273
29878
N74
N
S
R
R
I
A
T
N
S
W
H
H
H
L
V
Chicken
Gallus gallus
Q5ZMT9
252
27336
Q57
G
S
A
T
T
W
R
Q
H
L
V
Q
R
S
V
Frog
Xenopus laevis
Q6DF80
251
27551
R56
T
L
A
S
S
E
G
R
S
L
I
Q
R
S
L
Zebra Danio
Brachydanio rerio
Q8AV61
251
27578
A56
S
L
H
S
L
Q
S
A
N
L
I
R
R
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001201451
248
27492
L53
K
V
K
L
C
R
S
L
C
R
R
G
V
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
58.7
84.1
N.A.
79.4
80.1
N.A.
81.9
77.6
75
70.4
N.A.
N.A.
N.A.
N.A.
54.8
Protein Similarity:
100
99.6
61.9
87
N.A.
83.3
84.1
N.A.
86.6
80.8
80.5
79.7
N.A.
N.A.
N.A.
N.A.
66
P-Site Identity:
100
100
13.3
13.3
N.A.
0
0
N.A.
6.6
6.6
6.6
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
26.6
26.6
N.A.
0
0
N.A.
26.6
6.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
19
28
0
10
10
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
19
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
19
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
19
0
19
37
0
10
37
10
10
0
10
10
0
19
0
% G
% His:
0
0
10
0
0
0
19
19
10
0
10
10
10
10
28
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
19
0
0
0
0
% I
% Lys:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
19
0
10
10
0
0
10
0
46
0
0
0
10
55
% L
% Met:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
10
10
0
0
19
0
0
0
% N
% Pro:
0
0
19
19
10
19
0
0
19
19
28
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
10
0
0
0
37
0
0
0
% Q
% Arg:
0
19
19
10
0
10
19
10
0
10
10
10
46
0
0
% R
% Ser:
10
37
0
19
28
10
19
28
28
0
0
10
0
37
0
% S
% Thr:
10
0
0
10
10
0
10
0
0
0
0
0
19
0
0
% T
% Val:
0
10
0
0
0
0
0
0
0
0
28
10
19
10
19
% V
% Trp:
0
0
0
0
0
28
0
0
0
10
0
0
10
19
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
19
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _