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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR2D
All Species:
13.94
Human Site:
S18
Identified Species:
27.88
UniProt:
O15514
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15514
NP_004796.1
142
16311
S18
G
D
V
E
E
D
A
S
Q
L
I
F
P
K
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090528
142
16263
S18
G
D
V
E
E
D
A
S
Q
L
I
F
P
K
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
NP_081377
104
12248
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517684
133
15350
T19
C
F
L
S
K
F
E
T
A
E
T
L
L
N
S
Chicken
Gallus gallus
XP_422576
142
16307
S18
A
D
V
E
E
D
A
S
Q
L
V
F
P
K
E
Frog
Xenopus laevis
NP_001087315
142
16276
S18
G
D
A
E
E
D
A
S
Q
L
L
F
P
K
E
Zebra Danio
Brachydanio rerio
NP_001002317
141
16149
Q18
D
V
E
E
D
A
S
Q
L
M
F
P
K
E
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEA5
139
16194
Q18
D
E
D
A
A
D
L
Q
F
P
K
E
F
E
N
Honey Bee
Apis mellifera
XP_391932
580
67411
K456
A
Q
A
R
V
L
L
K
I
D
V
N
K
T
Q
Nematode Worm
Caenorhab. elegans
NP_495544
144
16511
C21
V
E
E
D
A
A
E
C
K
F
P
K
E
F
E
Sea Urchin
Strong. purpuratus
XP_795859
142
16580
V23
S
E
L
K
F
P
K
V
F
E
Q
A
E
T
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P20433
221
25396
D98
T
T
A
V
E
D
E
D
D
D
L
D
E
D
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.3
N.A.
N.A.
73.2
N.A.
N.A.
85.2
97.1
90.8
92.2
N.A.
72.5
21
57.6
76
Protein Similarity:
100
N.A.
99.3
N.A.
N.A.
73.2
N.A.
N.A.
87.3
98.5
97.8
95
N.A.
81.6
22.5
81.2
84.5
P-Site Identity:
100
N.A.
100
N.A.
N.A.
0
N.A.
N.A.
0
86.6
86.6
6.6
N.A.
6.6
0
6.6
0
P-Site Similarity:
100
N.A.
100
N.A.
N.A.
0
N.A.
N.A.
20
93.3
93.3
33.3
N.A.
20
13.3
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
25
9
17
17
34
0
9
0
0
9
0
0
0
% A
% Cys:
9
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
17
34
9
9
9
50
0
9
9
17
0
9
0
9
9
% D
% Glu:
0
25
17
42
42
0
25
0
0
17
0
9
25
17
42
% E
% Phe:
0
9
0
0
9
9
0
0
17
9
9
34
9
9
9
% F
% Gly:
25
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
17
0
0
0
0
% I
% Lys:
0
0
0
9
9
0
9
9
9
0
9
9
17
34
0
% K
% Leu:
0
0
17
0
0
9
17
0
9
34
17
9
9
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
9
% N
% Pro:
0
0
0
0
0
9
0
0
0
9
9
9
34
0
0
% P
% Gln:
0
9
0
0
0
0
0
17
34
0
9
0
0
0
9
% Q
% Arg:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
0
0
9
0
0
9
34
0
0
0
0
0
0
9
% S
% Thr:
9
9
0
0
0
0
0
9
0
0
9
0
0
17
0
% T
% Val:
9
9
25
9
9
0
0
9
0
0
17
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _