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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR2D
All Species:
22.73
Human Site:
S58
Identified Species:
45.45
UniProt:
O15514
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15514
NP_004796.1
142
16311
S58
A
E
D
E
Q
E
L
S
E
V
F
M
K
T
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090528
142
16263
S58
A
E
D
E
Q
E
L
S
E
V
F
M
K
T
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
NP_081377
104
12248
R32
K
T
L
N
Y
T
A
R
F
S
R
F
K
N
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517684
133
15350
T59
F
M
K
T
L
N
Y
T
A
R
F
S
R
F
K
Chicken
Gallus gallus
XP_422576
142
16307
S58
A
E
D
E
Q
E
L
S
E
V
F
M
K
T
L
Frog
Xenopus laevis
NP_001087315
142
16276
S58
A
E
E
E
Q
E
L
S
E
V
F
M
K
T
L
Zebra Danio
Brachydanio rerio
NP_001002317
141
16149
E58
E
D
E
Q
E
L
S
E
V
F
M
K
T
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEA5
139
16194
F58
E
Q
E
F
S
E
V
F
M
K
T
Y
A
Y
T
Honey Bee
Apis mellifera
XP_391932
580
67411
S496
A
E
E
E
Q
E
F
S
E
V
F
M
K
S
L
Nematode Worm
Caenorhab. elegans
NP_495544
144
16511
S61
K
D
E
I
E
E
M
S
E
V
F
I
K
T
L
Sea Urchin
Strong. purpuratus
XP_795859
142
16580
L63
S
E
V
F
M
K
T
L
N
Y
T
G
R
F
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P20433
221
25396
N138
E
Q
T
T
G
G
N
N
K
D
L
K
N
T
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.3
N.A.
N.A.
73.2
N.A.
N.A.
85.2
97.1
90.8
92.2
N.A.
72.5
21
57.6
76
Protein Similarity:
100
N.A.
99.3
N.A.
N.A.
73.2
N.A.
N.A.
87.3
98.5
97.8
95
N.A.
81.6
22.5
81.2
84.5
P-Site Identity:
100
N.A.
100
N.A.
N.A.
6.6
N.A.
N.A.
6.6
100
93.3
0
N.A.
6.6
80
53.3
6.6
P-Site Similarity:
100
N.A.
100
N.A.
N.A.
6.6
N.A.
N.A.
20
100
100
26.6
N.A.
26.6
93.3
86.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
42
0
0
0
0
0
9
0
9
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
17
25
0
0
0
0
0
0
9
0
0
0
0
0
% D
% Glu:
25
50
42
42
17
59
0
9
50
0
0
0
0
0
0
% E
% Phe:
9
0
0
17
0
0
9
9
9
9
59
9
0
17
0
% F
% Gly:
0
0
0
0
9
9
0
0
0
0
0
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
0
0
0
0
0
9
0
0
0
% I
% Lys:
17
0
9
0
0
9
0
0
9
9
0
17
59
0
9
% K
% Leu:
0
0
9
0
9
9
34
9
0
0
9
0
0
9
50
% L
% Met:
0
9
0
0
9
0
9
0
9
0
9
42
0
0
9
% M
% Asn:
0
0
0
9
0
9
9
9
9
0
0
0
9
9
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
17
0
9
42
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
9
0
9
9
0
17
0
9
% R
% Ser:
9
0
0
0
9
0
9
50
0
9
0
9
0
9
9
% S
% Thr:
0
9
9
17
0
9
9
9
0
0
17
0
9
50
9
% T
% Val:
0
0
9
0
0
0
9
0
9
50
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
9
0
0
9
0
9
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _