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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR2D
All Species:
3.85
Human Site:
S6
Identified Species:
7.69
UniProt:
O15514
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15514
NP_004796.1
142
16311
S6
_
_
M
A
A
G
G
S
D
P
R
A
G
D
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090528
142
16263
G6
_
_
M
A
A
G
G
G
D
P
R
A
G
D
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
NP_081377
104
12248
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517684
133
15350
R7
_
I
L
G
G
I
S
R
A
L
S
V
C
F
L
Chicken
Gallus gallus
XP_422576
142
16307
S6
_
_
M
A
A
G
G
S
D
P
R
T
A
D
V
Frog
Xenopus laevis
NP_001087315
142
16276
A6
_
_
M
A
A
G
G
A
E
T
H
S
G
D
A
Zebra Danio
Brachydanio rerio
NP_001002317
141
16149
A6
_
_
M
A
A
A
G
A
T
Q
V
G
D
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEA5
139
16194
P6
_
_
M
S
F
M
N
P
V
D
M
V
D
E
D
Honey Bee
Apis mellifera
XP_391932
580
67411
G444
I
A
E
N
K
K
S
G
C
L
R
L
A
Q
A
Nematode Worm
Caenorhab. elegans
NP_495544
144
16511
K9
S
S
G
G
G
N
Q
K
S
D
G
Q
V
E
E
Sea Urchin
Strong. purpuratus
XP_795859
142
16580
Q11
F
I
P
G
Q
E
E
Q
E
E
D
A
S
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P20433
221
25396
N86
K
K
H
L
K
H
E
N
A
N
D
E
T
T
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.3
N.A.
N.A.
73.2
N.A.
N.A.
85.2
97.1
90.8
92.2
N.A.
72.5
21
57.6
76
Protein Similarity:
100
N.A.
99.3
N.A.
N.A.
73.2
N.A.
N.A.
87.3
98.5
97.8
95
N.A.
81.6
22.5
81.2
84.5
P-Site Identity:
100
N.A.
92.3
N.A.
N.A.
0
N.A.
N.A.
0
84.6
53.8
30.7
N.A.
7.6
6.6
0
6.6
P-Site Similarity:
100
N.A.
92.3
N.A.
N.A.
0
N.A.
N.A.
21.4
84.6
76.9
38.4
N.A.
23
13.3
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
42
42
9
0
17
17
0
0
25
17
0
25
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
25
17
17
0
17
34
9
% D
% Glu:
0
0
9
0
0
9
17
0
17
9
0
9
0
25
17
% E
% Phe:
9
0
0
0
9
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
0
0
9
25
17
34
42
17
0
0
9
9
25
0
0
% G
% His:
0
0
9
0
0
9
0
0
0
0
9
0
0
0
0
% H
% Ile:
9
17
0
0
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
9
0
0
17
9
0
9
0
0
0
0
0
0
0
% K
% Leu:
0
0
9
9
0
0
0
0
0
17
0
9
0
0
17
% L
% Met:
0
0
50
0
0
9
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
9
0
9
9
9
0
9
0
0
0
0
0
% N
% Pro:
0
0
9
0
0
0
0
9
0
25
0
0
0
0
0
% P
% Gln:
0
0
0
0
9
0
9
9
0
9
0
9
0
9
0
% Q
% Arg:
0
0
0
0
0
0
0
9
0
0
34
0
0
0
0
% R
% Ser:
9
9
0
9
0
0
17
17
9
0
9
9
9
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
9
9
0
9
9
9
0
% T
% Val:
0
0
0
0
0
0
0
0
9
0
9
17
9
9
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
59
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% _