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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR2D
All Species:
14.85
Human Site:
S82
Identified Species:
29.7
UniProt:
O15514
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15514
NP_004796.1
142
16311
S82
K
N
R
E
T
I
A
S
V
R
S
L
L
L
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090528
142
16263
S82
K
N
R
E
T
I
A
S
V
R
S
L
L
L
Q
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
NP_081377
104
12248
K56
L
L
Q
K
K
L
H
K
F
E
L
A
C
L
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517684
133
15350
L83
S
L
L
L
Q
K
K
L
H
K
F
E
L
A
C
Chicken
Gallus gallus
XP_422576
142
16307
S82
K
N
R
E
T
I
A
S
V
R
S
L
L
L
Q
Frog
Xenopus laevis
NP_001087315
142
16276
S82
K
N
R
E
T
I
A
S
V
R
S
L
L
L
Q
Zebra Danio
Brachydanio rerio
NP_001002317
141
16149
V82
N
R
E
T
I
A
S
V
R
S
L
L
L
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEA5
139
16194
S82
E
T
I
M
S
A
R
S
L
L
M
Q
K
K
L
Honey Bee
Apis mellifera
XP_391932
580
67411
A520
K
N
K
E
T
I
A
A
V
R
N
L
L
M
Q
Nematode Worm
Caenorhab. elegans
NP_495544
144
16511
A85
K
N
R
E
T
I
R
A
V
R
A
I
F
S
E
Sea Urchin
Strong. purpuratus
XP_795859
142
16580
Q87
D
V
R
G
L
L
Q
Q
Q
Q
P
K
L
H
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P20433
221
25396
A162
R
D
Q
E
T
V
G
A
V
I
Q
L
L
K
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.3
N.A.
N.A.
73.2
N.A.
N.A.
85.2
97.1
90.8
92.2
N.A.
72.5
21
57.6
76
Protein Similarity:
100
N.A.
99.3
N.A.
N.A.
73.2
N.A.
N.A.
87.3
98.5
97.8
95
N.A.
81.6
22.5
81.2
84.5
P-Site Identity:
100
N.A.
100
N.A.
N.A.
6.6
N.A.
N.A.
6.6
100
100
13.3
N.A.
6.6
73.3
53.3
13.3
P-Site Similarity:
100
N.A.
100
N.A.
N.A.
26.6
N.A.
N.A.
13.3
100
100
26.6
N.A.
26.6
100
80
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
17
42
25
0
0
9
9
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% C
% Asp:
9
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
9
59
0
0
0
0
0
9
0
9
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
9
0
9
0
0
% F
% Gly:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
9
0
9
0
0
0
0
9
0
% H
% Ile:
0
0
9
0
9
50
0
0
0
9
0
9
0
0
0
% I
% Lys:
50
0
9
9
9
9
9
9
0
9
0
9
9
17
17
% K
% Leu:
9
17
9
9
9
17
0
9
9
9
17
59
75
42
9
% L
% Met:
0
0
0
9
0
0
0
0
0
0
9
0
0
9
0
% M
% Asn:
9
50
0
0
0
0
0
0
0
0
9
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% P
% Gln:
0
0
17
0
9
0
9
9
9
9
9
9
0
9
42
% Q
% Arg:
9
9
50
0
0
0
17
0
9
50
0
0
0
0
0
% R
% Ser:
9
0
0
0
9
0
9
42
0
9
34
0
0
9
9
% S
% Thr:
0
9
0
9
59
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
9
0
0
0
9
0
9
59
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _