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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CFLAR
All Species:
18.48
Human Site:
S419
Identified Species:
45.19
UniProt:
O15519
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15519
NP_001120655.1
480
55344
S419
L
L
E
Q
S
H
S
S
P
S
L
Y
L
Q
C
Chimpanzee
Pan troglodytes
XP_001171615
480
55346
S419
L
L
E
Q
S
H
S
S
P
S
L
Y
L
Q
C
Rhesus Macaque
Macaca mulatta
XP_001096860
300
34118
M246
I
P
E
E
R
Y
K
M
K
S
K
P
L
G
I
Dog
Lupus familis
XP_545592
509
58483
S448
L
L
E
Q
S
S
G
S
P
S
L
Y
L
K
C
Cat
Felis silvestris
Mouse
Mus musculus
O35732
484
55227
S423
H
L
E
K
P
S
S
S
S
S
V
Y
L
Q
K
Rat
Rattus norvegicus
NP_001029036
480
55041
S419
R
L
E
Q
P
S
S
S
L
S
V
Y
L
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507915
508
56290
S445
V
L
E
R
P
P
G
S
V
S
F
Y
L
R
T
Chicken
Gallus gallus
Q98943
424
47941
S369
T
T
V
F
A
E
D
S
R
D
T
H
V
A
D
Frog
Xenopus laevis
NP_001079034
500
57605
N435
T
S
L
R
H
R
E
N
G
S
I
Y
I
Q
Q
Zebra Danio
Brachydanio rerio
NP_919380
418
47600
D364
P
V
M
P
S
M
D
D
E
Y
L
E
T
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
58.3
73.2
N.A.
66.7
68.7
N.A.
48.2
20.4
26.2
30.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
60.4
82.1
N.A.
78
79.5
N.A.
64.1
40
46.7
51
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
20
80
N.A.
53.3
60
N.A.
40
6.6
20
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
40
86.6
N.A.
66.6
66.6
N.A.
60
26.6
46.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
30
% C
% Asp:
0
0
0
0
0
0
20
10
0
10
0
0
0
10
10
% D
% Glu:
0
0
70
10
0
10
10
0
10
0
0
10
0
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
20
0
10
0
0
0
0
10
0
% G
% His:
10
0
0
0
10
20
0
0
0
0
0
10
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
10
0
10
0
10
% I
% Lys:
0
0
0
10
0
0
10
0
10
0
10
0
0
10
20
% K
% Leu:
30
60
10
0
0
0
0
0
10
0
40
0
70
0
0
% L
% Met:
0
0
10
0
0
10
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
10
10
0
10
30
10
0
0
30
0
0
10
0
0
0
% P
% Gln:
0
0
0
40
0
0
0
0
0
0
0
0
0
50
10
% Q
% Arg:
10
0
0
20
10
10
0
0
10
0
0
0
0
10
0
% R
% Ser:
0
10
0
0
40
30
40
70
10
80
0
0
0
0
0
% S
% Thr:
20
10
0
0
0
0
0
0
0
0
10
0
10
0
10
% T
% Val:
10
10
10
0
0
0
0
0
10
0
20
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
10
0
70
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _