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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX3Y All Species: 27.58
Human Site: S490 Identified Species: 43.33
UniProt: O15523 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15523 NP_001116137.1 660 73154 S490 H Q F R S G K S P I L V A T A
Chimpanzee Pan troglodytes Q6GVM6 660 73172 S490 H Q F R S G K S P I L V A T A
Rhesus Macaque Macaca mulatta XP_001095294 910 100218 S742 H Q F R S G K S P I L V A T A
Dog Lupus familis XP_861268 662 73195 S492 H Q F R S G K S P I L V A T A
Cat Felis silvestris
Mouse Mus musculus Q62095 658 73409 S488 E A L H Q F R S G R K P I L V
Rat Rattus norvegicus NP_001102328 659 72976 S490 H Q F R S G K S P I L V A T A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512924 651 71975 S478 H Q F R S G K S P I L V A T A
Chicken Gallus gallus NP_001025971 651 72031 S481 E A L H Q F R S G K S P I L V
Frog Xenopus laevis P24346 697 77284 Q527 D R E E A L H Q F R S G K S P
Zebra Danio Brachydanio rerio NP_571016 688 75828 R512 G D R S Q R D R E E A L H Q F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VHP0 798 85063 C610 R C F R S G D C P I L V A T A
Honey Bee Apis mellifera XP_391829 701 78642 F530 R E D A L R R F R A G K A P I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M2F9 646 69224 T456 R S F K T G R T P I L V A T D
Baker's Yeast Sacchar. cerevisiae P24784 617 67899 E449 H G D R T Q A E R E R A L S A
Red Bread Mold Neurospora crassa Q9P6U9 688 72037 C504 E M F R N G R C P I L V A T A
Conservation
Percent
Protein Identity: 100 98.3 64.9 91.6 N.A. 89 89.6 N.A. 90.3 86.9 79.3 74.5 N.A. 51.8 58 N.A. N.A.
Protein Similarity: 100 99.2 68.3 95.6 N.A. 94 94.6 N.A. 94.8 91.8 86.2 83.2 N.A. 63 69.9 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 6.6 100 N.A. 100 6.6 0 0 N.A. 73.3 6.6 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 13.3 100 N.A. 100 13.3 20 6.6 N.A. 73.3 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 50.3 50.1 53
Protein Similarity: N.A. N.A. N.A. 65 65.6 65.4
P-Site Identity: N.A. N.A. N.A. 53.3 20 66.6
P-Site Similarity: N.A. N.A. N.A. 80 33.3 80
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 14 0 7 7 0 7 0 0 7 7 7 67 0 60 % A
% Cys: 0 7 0 0 0 0 0 14 0 0 0 0 0 0 0 % C
% Asp: 7 7 14 0 0 0 14 0 0 0 0 0 0 0 7 % D
% Glu: 20 7 7 7 0 0 0 7 7 14 0 0 0 0 0 % E
% Phe: 0 0 60 0 0 14 0 7 7 0 0 0 0 0 7 % F
% Gly: 7 7 0 0 0 60 0 0 14 0 7 7 0 0 0 % G
% His: 47 0 0 14 0 0 7 0 0 0 0 0 7 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 60 0 0 14 0 7 % I
% Lys: 0 0 0 7 0 0 40 0 0 7 7 7 7 0 0 % K
% Leu: 0 0 14 0 7 7 0 0 0 0 60 7 7 14 0 % L
% Met: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 60 0 0 14 0 7 7 % P
% Gln: 0 40 0 0 20 7 0 7 0 0 0 0 0 7 0 % Q
% Arg: 20 7 7 60 0 14 34 7 14 14 7 0 0 0 0 % R
% Ser: 0 7 0 7 47 0 0 54 0 0 14 0 0 14 0 % S
% Thr: 0 0 0 0 14 0 0 7 0 0 0 0 0 60 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 60 0 0 14 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _