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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX3Y All Species: 16.06
Human Site: S588 Identified Species: 25.24
UniProt: O15523 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.36
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15523 NP_001116137.1 660 73154 S588 G S R G R S K S N R F S G G F
Chimpanzee Pan troglodytes Q6GVM6 660 73172 S588 G S R G R S K S N R F S G G F
Rhesus Macaque Macaca mulatta XP_001095294 910 100218 K839 G S S R G R S K S S R F S G G
Dog Lupus familis XP_861268 662 73195 S590 S S R G R S K S S R F S G G F
Cat Felis silvestris
Mouse Mus musculus Q62095 658 73409 R586 Y K G S S R G R S K S R F S G
Rat Rattus norvegicus NP_001102328 659 72976 K587 G G S R G R S K S R F S G G F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512924 651 71975 S576 S S R G R S K S S R F S G G F
Chicken Gallus gallus NP_001025971 651 72031 G579 H K G G G S R G R S K S R F T
Frog Xenopus laevis P24346 697 77284 S625 E Q H H K S S S R G R S K S R
Zebra Danio Brachydanio rerio NP_571016 688 75828 S616 E H Q H K S S S R G R S K R F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VHP0 798 85063 G709 K R A G R G G G G R Y G G G F
Honey Bee Apis mellifera XP_391829 701 78642 R630 Y S G G G S R R A G S T K G R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M2F9 646 69224 G554 G K N R R S G G R F G G R D F
Baker's Yeast Sacchar. cerevisiae P24784 617 67899 R546 T F L S D L S R Q N S R G G R
Red Bread Mold Neurospora crassa Q9P6U9 688 72037 G602 G R G G R G G G R G G G R G R
Conservation
Percent
Protein Identity: 100 98.3 64.9 91.6 N.A. 89 89.6 N.A. 90.3 86.9 79.3 74.5 N.A. 51.8 58 N.A. N.A.
Protein Similarity: 100 99.2 68.3 95.6 N.A. 94 94.6 N.A. 94.8 91.8 86.2 83.2 N.A. 63 69.9 N.A. N.A.
P-Site Identity: 100 100 20 86.6 N.A. 0 46.6 N.A. 86.6 20 20 26.6 N.A. 40 26.6 N.A. N.A.
P-Site Similarity: 100 100 26.6 93.3 N.A. 13.3 53.3 N.A. 93.3 26.6 26.6 40 N.A. 46.6 40 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 50.3 50.1 53
Protein Similarity: N.A. N.A. N.A. 65 65.6 65.4
P-Site Identity: N.A. N.A. N.A. 26.6 13.3 26.6
P-Site Similarity: N.A. N.A. N.A. 26.6 13.3 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 0 0 0 0 7 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 7 0 0 0 0 0 0 0 0 7 0 % D
% Glu: 14 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 7 0 0 0 0 0 0 0 7 34 7 7 7 54 % F
% Gly: 40 7 27 54 27 14 27 27 7 27 14 20 47 67 14 % G
% His: 7 7 7 14 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 7 20 0 0 14 0 27 14 0 7 7 0 20 0 0 % K
% Leu: 0 0 7 0 0 7 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 7 0 0 0 0 0 14 7 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 7 7 0 0 0 0 0 7 0 0 0 0 0 0 % Q
% Arg: 0 14 27 20 47 20 14 20 34 40 20 14 20 7 27 % R
% Ser: 14 40 14 14 7 60 34 40 34 14 20 54 7 14 0 % S
% Thr: 7 0 0 0 0 0 0 0 0 0 0 7 0 0 7 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 14 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _