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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP27B1
All Species:
30.61
Human Site:
T218
Identified Species:
74.81
UniProt:
O15528
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15528
NP_000776.1
508
56504
T218
E
A
Q
V
P
P
D
T
E
T
F
I
R
A
V
Chimpanzee
Pan troglodytes
XP_509175
508
56515
T218
E
A
Q
V
P
P
D
T
E
T
F
I
R
A
V
Rhesus Macaque
Macaca mulatta
XP_001116450
508
56650
T218
E
A
Q
V
P
P
D
T
E
T
F
I
R
A
V
Dog
Lupus familis
XP_538254
535
58293
T245
E
A
Q
V
P
P
D
T
D
A
F
I
R
A
V
Cat
Felis silvestris
Mouse
Mus musculus
O35084
507
56206
T218
E
A
E
V
P
P
D
T
E
T
F
I
H
A
V
Rat
Rattus norvegicus
O35132
501
55350
T211
E
A
E
V
P
P
D
T
E
T
F
I
E
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422077
536
61257
T245
E
N
N
V
P
Q
Q
T
V
E
Y
I
E
A
L
Frog
Xenopus laevis
NP_001087098
542
61748
T251
E
K
Q
T
P
P
E
T
Q
K
F
I
D
S
I
Zebra Danio
Brachydanio rerio
NP_001116749
513
58741
T226
N
D
E
I
P
E
E
T
Q
K
F
I
F
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V5L3
589
65883
A291
S
P
E
G
S
E
E
A
Q
Q
I
I
E
A
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96.2
83.9
N.A.
81.5
81.5
N.A.
N.A.
41.4
38.1
40.7
N.A.
27.3
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
97.4
87.6
N.A.
88.5
89.3
N.A.
N.A.
58.9
57.9
62.7
N.A.
42.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
N.A.
40
46.6
33.3
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
53.3
73.3
66.6
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
60
0
0
0
0
0
10
0
10
0
0
0
80
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
60
0
10
0
0
0
10
0
0
% D
% Glu:
80
0
40
0
0
20
30
0
50
10
0
0
30
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
80
0
10
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
10
100
0
0
20
% I
% Lys:
0
10
0
0
0
0
0
0
0
20
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
90
70
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
50
0
0
10
10
0
30
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
40
0
0
% R
% Ser:
10
0
0
0
10
0
0
0
0
0
0
0
0
20
0
% S
% Thr:
0
0
0
10
0
0
0
90
0
50
0
0
0
0
0
% T
% Val:
0
0
0
70
0
0
0
0
10
0
0
0
0
0
70
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _