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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDPK1
All Species:
18.48
Human Site:
S22
Identified Species:
33.89
UniProt:
O15530
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15530
NP_002604.1
556
63152
S22
Q
S
S
V
V
L
C
S
C
P
S
P
S
M
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537000
560
63701
S24
Q
S
S
V
V
L
C
S
C
P
S
P
S
M
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2A0
559
63740
S22
Q
S
S
V
V
L
C
S
C
P
S
P
S
M
V
Rat
Rattus norvegicus
O55173
559
63591
S22
Q
S
S
V
V
L
C
S
C
P
S
P
S
M
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518589
320
36424
Chicken
Gallus gallus
Q6U1I9
432
48872
Frog
Xenopus laevis
Q6GPN6
434
49096
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W0V1
836
94060
H63
C
S
S
N
G
T
E
H
Q
Q
H
F
N
I
A
Honey Bee
Apis mellifera
XP_394208
537
61368
T33
T
T
N
P
A
L
T
T
I
N
P
P
T
H
K
Nematode Worm
Caenorhab. elegans
Q9Y1J3
636
71898
S22
T
T
N
N
D
T
T
S
D
R
E
A
A
P
T
Sea Urchin
Strong. purpuratus
XP_786576
539
61612
S23
I
H
S
P
V
S
R
S
C
H
Q
E
A
M
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12236
1081
121642
K62
V
G
D
L
L
L
E
K
R
T
A
K
P
M
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
93.3
N.A.
94.8
95.3
N.A.
52.1
28.6
28
27.5
N.A.
32.5
54.1
32.5
58
Protein Similarity:
100
N.A.
N.A.
95
N.A.
96.2
96.4
N.A.
54.6
44
43.8
43.3
N.A.
44.1
66.1
52.2
70.3
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
0
0
0
0
N.A.
13.3
13.3
6.6
33.3
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
0
0
0
0
N.A.
26.6
40
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
0
8
8
16
0
8
% A
% Cys:
8
0
0
0
0
0
31
0
39
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
8
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
16
0
0
0
8
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
8
0
8
8
0
0
8
0
% H
% Ile:
8
0
0
0
0
0
0
0
8
0
0
0
0
8
8
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
8
% K
% Leu:
0
0
0
8
8
47
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
47
0
% M
% Asn:
0
0
16
16
0
0
0
0
0
8
0
0
8
0
0
% N
% Pro:
0
0
0
16
0
0
0
0
0
31
8
39
8
8
0
% P
% Gln:
31
0
0
0
0
0
0
0
8
8
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
8
8
0
0
0
0
0
% R
% Ser:
0
39
47
0
0
8
0
47
0
0
31
0
31
0
8
% S
% Thr:
16
16
0
0
0
16
16
8
0
8
0
0
8
0
8
% T
% Val:
8
0
0
31
39
0
0
0
0
0
0
0
0
0
31
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _