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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDPK1 All Species: 30.3
Human Site: S250 Identified Species: 55.56
UniProt: O15530 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15530 NP_002604.1 556 63152 S250 V G T A Q Y V S P E L L T E K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537000 560 63701 S254 V G T A Q Y V S P E L L T E K
Cat Felis silvestris
Mouse Mus musculus Q9Z2A0 559 63740 S253 V G T A Q Y V S P E L L T E K
Rat Rattus norvegicus O55173 559 63591 S253 V G T A Q Y V S P E L L T E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518589 320 36424 K59 F T F Q D D E K L Y F G L S Y
Chicken Gallus gallus Q6U1I9 432 48872 D171 H F S F Q T A D K L Y F V L D
Frog Xenopus laevis Q6GPN6 434 49096 S173 H F S F Q T T S R L Y F I L D
Zebra Danio Brachydanio rerio Q7ZTW4 433 48964 D172 H Y S F Q T T D K L Y F V L D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W0V1 836 94060 S478 V G T A Q Y V S P E V L Q N G
Honey Bee Apis mellifera XP_394208 537 61368 V244 F V G T A Q Y V S P E L L T D
Nematode Worm Caenorhab. elegans Q9Y1J3 636 71898 S278 V G T A L Y V S P E M L A D G
Sea Urchin Strong. purpuratus XP_786576 539 61612 S255 V G T A Q Y V S P E L L T E K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12236 1081 121642 S357 V G T A E Y V S P E L L N D S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 93.3 N.A. 94.8 95.3 N.A. 52.1 28.6 28 27.5 N.A. 32.5 54.1 32.5 58
Protein Similarity: 100 N.A. N.A. 95 N.A. 96.2 96.4 N.A. 54.6 44 43.8 43.3 N.A. 44.1 66.1 52.2 70.3
P-Site Identity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 0 6.6 13.3 6.6 N.A. 73.3 6.6 66.6 100
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 0 13.3 20 13.3 N.A. 80 6.6 80 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 35.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 73.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 86.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 62 8 0 8 0 0 0 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 8 0 16 0 0 0 0 0 16 31 % D
% Glu: 0 0 0 0 8 0 8 0 0 62 8 0 0 39 0 % E
% Phe: 16 16 8 24 0 0 0 0 0 0 8 24 0 0 0 % F
% Gly: 0 62 8 0 0 0 0 0 0 0 0 8 0 0 16 % G
% His: 24 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % I
% Lys: 0 0 0 0 0 0 0 8 16 0 0 0 0 0 39 % K
% Leu: 0 0 0 0 8 0 0 0 8 24 47 70 16 24 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % N
% Pro: 0 0 0 0 0 0 0 0 62 8 0 0 0 0 0 % P
% Gln: 0 0 0 8 70 8 0 0 0 0 0 0 8 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % R
% Ser: 0 0 24 0 0 0 0 70 8 0 0 0 0 8 8 % S
% Thr: 0 8 62 8 0 24 16 0 0 0 0 0 39 8 0 % T
% Val: 62 8 0 0 0 0 62 8 0 0 8 0 16 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 62 8 0 0 8 24 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _