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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDPK1
All Species:
15.15
Human Site:
S389
Identified Species:
27.78
UniProt:
O15530
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15530
NP_002604.1
556
63152
S389
Q
F
G
C
M
Q
V
S
S
S
S
S
S
H
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537000
560
63701
S393
Q
F
G
C
M
Q
V
S
S
S
S
S
S
H
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2A0
559
63740
S392
Q
F
G
F
M
Q
V
S
S
S
S
S
S
H
S
Rat
Rattus norvegicus
O55173
559
63591
S392
Q
F
G
C
M
Q
V
S
S
S
S
S
S
H
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518589
320
36424
G190
G
L
P
P
F
R
A
G
N
E
Y
L
I
F
Q
Chicken
Gallus gallus
Q6U1I9
432
48872
N302
L
P
P
F
Y
S
R
N
T
A
E
M
Y
D
N
Frog
Xenopus laevis
Q6GPN6
434
49096
N304
L
P
P
F
Y
S
R
N
T
A
E
M
Y
D
N
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
N303
L
P
P
F
Y
S
R
N
T
A
E
M
Y
D
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W0V1
836
94060
Q618
E
P
G
L
D
E
R
Q
I
S
R
L
L
S
A
Honey Bee
Apis mellifera
XP_394208
537
61368
Q385
E
P
G
L
D
D
K
Q
L
T
R
L
L
G
L
Nematode Worm
Caenorhab. elegans
Q9Y1J3
636
71898
N417
F
R
L
M
N
L
G
N
D
A
S
A
S
Q
P
Sea Urchin
Strong. purpuratus
XP_786576
539
61612
E394
L
N
P
T
S
L
S
E
Y
L
K
R
I
E
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12236
1081
121642
T847
I
K
K
L
F
H
P
T
S
A
A
E
T
L
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
93.3
N.A.
94.8
95.3
N.A.
52.1
28.6
28
27.5
N.A.
32.5
54.1
32.5
58
Protein Similarity:
100
N.A.
N.A.
95
N.A.
96.2
96.4
N.A.
54.6
44
43.8
43.3
N.A.
44.1
66.1
52.2
70.3
P-Site Identity:
100
N.A.
N.A.
100
N.A.
93.3
100
N.A.
0
0
0
0
N.A.
13.3
6.6
13.3
0
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
93.3
100
N.A.
13.3
26.6
26.6
26.6
N.A.
33.3
20
33.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
39
8
8
0
0
8
% A
% Cys:
0
0
0
24
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
16
8
0
0
8
0
0
0
0
24
0
% D
% Glu:
16
0
0
0
0
8
0
8
0
8
24
8
0
8
0
% E
% Phe:
8
31
0
31
16
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
8
0
47
0
0
0
8
8
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
31
0
% H
% Ile:
8
0
0
0
0
0
0
0
8
0
0
0
16
0
0
% I
% Lys:
0
8
8
0
0
0
8
0
0
0
8
0
0
0
0
% K
% Leu:
31
8
8
24
0
16
0
0
8
8
0
24
16
8
8
% L
% Met:
0
0
0
8
31
0
0
0
0
0
0
24
0
0
0
% M
% Asn:
0
8
0
0
8
0
0
31
8
0
0
0
0
0
24
% N
% Pro:
0
39
39
8
0
0
8
0
0
0
0
0
0
0
8
% P
% Gln:
31
0
0
0
0
31
0
16
0
0
0
0
0
8
8
% Q
% Arg:
0
8
0
0
0
8
31
0
0
0
16
8
0
0
0
% R
% Ser:
0
0
0
0
8
24
8
31
39
39
39
31
39
8
39
% S
% Thr:
0
0
0
8
0
0
0
8
24
8
0
0
8
0
8
% T
% Val:
0
0
0
0
0
0
31
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
24
0
0
0
8
0
8
0
24
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _