KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDPK1
All Species:
3.94
Human Site:
S400
Identified Species:
7.22
UniProt:
O15530
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15530
NP_002604.1
556
63152
S400
S
S
H
S
L
S
A
S
D
T
G
L
P
Q
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537000
560
63701
S404
S
S
H
S
L
S
A
S
D
A
G
L
P
Q
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2A0
559
63740
V403
S
S
H
S
L
S
T
V
E
T
S
L
P
Q
R
Rat
Rattus norvegicus
O55173
559
63591
V403
S
S
H
S
L
C
A
V
D
A
S
L
P
Q
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518589
320
36424
K201
L
I
F
Q
K
I
I
K
L
E
Y
D
F
P
E
Chicken
Gallus gallus
Q6U1I9
432
48872
K313
M
Y
D
N
I
L
N
K
P
L
Q
L
K
P
N
Frog
Xenopus laevis
Q6GPN6
434
49096
K315
M
Y
D
N
I
L
N
K
P
L
Q
L
K
P
N
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
K314
M
Y
D
N
I
L
N
K
P
L
Q
L
K
P
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W0V1
836
94060
V629
L
L
S
A
E
L
G
V
G
S
S
V
A
M
P
Honey Bee
Apis mellifera
XP_394208
537
61368
E396
L
L
G
L
G
I
G
E
A
R
R
T
K
I
T
Nematode Worm
Caenorhab. elegans
Q9Y1J3
636
71898
R428
A
S
Q
P
S
T
F
R
P
S
N
V
E
H
R
Sea Urchin
Strong. purpuratus
XP_786576
539
61612
P405
R
I
E
T
H
D
R
P
H
S
P
T
R
D
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12236
1081
121642
E858
E
T
L
S
S
S
D
E
K
T
K
Y
Y
K
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
93.3
N.A.
94.8
95.3
N.A.
52.1
28.6
28
27.5
N.A.
32.5
54.1
32.5
58
Protein Similarity:
100
N.A.
N.A.
95
N.A.
96.2
96.4
N.A.
54.6
44
43.8
43.3
N.A.
44.1
66.1
52.2
70.3
P-Site Identity:
100
N.A.
N.A.
86.6
N.A.
73.3
73.3
N.A.
0
6.6
6.6
6.6
N.A.
0
0
13.3
0
P-Site Similarity:
100
N.A.
N.A.
86.6
N.A.
80
73.3
N.A.
0
20
20
20
N.A.
20
0
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
24
0
8
16
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
24
0
0
8
8
0
24
0
0
8
0
8
0
% D
% Glu:
8
0
8
0
8
0
0
16
8
8
0
0
8
0
8
% E
% Phe:
0
0
8
0
0
0
8
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
8
0
8
0
16
0
8
0
16
0
0
0
0
% G
% His:
0
0
31
0
8
0
0
0
8
0
0
0
0
8
0
% H
% Ile:
0
16
0
0
24
16
8
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
8
0
0
31
8
0
8
0
31
8
0
% K
% Leu:
24
16
8
8
31
31
0
0
8
24
0
54
0
0
0
% L
% Met:
24
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% M
% Asn:
0
0
0
24
0
0
24
0
0
0
8
0
0
0
31
% N
% Pro:
0
0
0
8
0
0
0
8
31
0
8
0
31
31
8
% P
% Gln:
0
0
8
8
0
0
0
0
0
0
24
0
0
31
0
% Q
% Arg:
8
0
0
0
0
0
8
8
0
8
8
0
8
0
39
% R
% Ser:
31
39
8
39
16
31
0
16
0
24
24
0
0
0
0
% S
% Thr:
0
8
0
8
0
8
8
0
0
24
0
16
0
0
8
% T
% Val:
0
0
0
0
0
0
0
24
0
0
0
16
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
24
0
0
0
0
0
0
0
0
8
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _