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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDPK1
All Species:
13.64
Human Site:
S410
Identified Species:
25
UniProt:
O15530
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15530
NP_002604.1
556
63152
S410
G
L
P
Q
R
S
G
S
N
I
E
Q
Y
I
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537000
560
63701
S414
G
L
P
Q
M
A
G
S
N
I
E
Q
Y
I
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2A0
559
63740
S413
S
L
P
Q
R
S
G
S
N
I
E
Q
Y
I
H
Rat
Rattus norvegicus
O55173
559
63591
S413
S
L
P
Q
R
S
G
S
N
I
E
Q
Y
I
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518589
320
36424
F211
Y
D
F
P
E
K
F
F
P
K
A
K
D
L
V
Chicken
Gallus gallus
Q6U1I9
432
48872
N323
Q
L
K
P
N
I
T
N
S
A
R
H
L
L
E
Frog
Xenopus laevis
Q6GPN6
434
49096
N325
Q
L
K
P
N
I
T
N
S
A
R
N
L
L
E
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
N324
Q
L
K
P
N
I
S
N
A
A
R
H
L
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W0V1
836
94060
R639
S
V
A
M
P
V
K
R
S
T
A
K
N
S
F
Honey Bee
Apis mellifera
XP_394208
537
61368
S406
R
T
K
I
T
T
S
S
D
G
N
I
A
D
L
Nematode Worm
Caenorhab. elegans
Q9Y1J3
636
71898
P438
N
V
E
H
R
G
D
P
F
V
S
E
I
A
P
Sea Urchin
Strong. purpuratus
XP_786576
539
61612
V415
P
T
R
D
N
K
Y
V
V
D
L
T
P
A
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12236
1081
121642
V868
K
Y
Y
K
R
T
I
V
M
T
S
F
G
R
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
93.3
N.A.
94.8
95.3
N.A.
52.1
28.6
28
27.5
N.A.
32.5
54.1
32.5
58
Protein Similarity:
100
N.A.
N.A.
95
N.A.
96.2
96.4
N.A.
54.6
44
43.8
43.3
N.A.
44.1
66.1
52.2
70.3
P-Site Identity:
100
N.A.
N.A.
86.6
N.A.
93.3
93.3
N.A.
0
6.6
6.6
6.6
N.A.
0
6.6
6.6
0
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
93.3
93.3
N.A.
13.3
26.6
26.6
20
N.A.
20
20
26.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
8
0
0
8
24
16
0
8
16
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
0
0
8
0
8
8
0
0
8
8
0
% D
% Glu:
0
0
8
0
8
0
0
0
0
0
31
8
0
0
31
% E
% Phe:
0
0
8
0
0
0
8
8
8
0
0
8
0
0
16
% F
% Gly:
16
0
0
0
0
8
31
0
0
8
0
0
8
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
16
0
0
31
% H
% Ile:
0
0
0
8
0
24
8
0
0
31
0
8
8
31
0
% I
% Lys:
8
0
31
8
0
16
8
0
0
8
0
16
0
0
0
% K
% Leu:
0
54
0
0
0
0
0
0
0
0
8
0
24
31
8
% L
% Met:
0
0
0
8
8
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
31
0
0
24
31
0
8
8
8
0
0
% N
% Pro:
8
0
31
31
8
0
0
8
8
0
0
0
8
0
8
% P
% Gln:
24
0
0
31
0
0
0
0
0
0
0
31
0
0
0
% Q
% Arg:
8
0
8
0
39
0
0
8
0
0
24
0
0
8
0
% R
% Ser:
24
0
0
0
0
24
16
39
24
0
16
0
0
8
0
% S
% Thr:
0
16
0
0
8
16
16
0
0
16
0
8
0
0
0
% T
% Val:
0
16
0
0
0
8
0
16
8
8
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
8
0
0
0
8
0
0
0
0
0
31
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _