Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDPK1 All Species: 21.21
Human Site: T180 Identified Species: 38.89
UniProt: O15530 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15530 NP_002604.1 556 63152 T180 K I G S F D E T C T R F Y T A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537000 560 63701 T184 K I G S F D E T C T R F Y T A
Cat Felis silvestris
Mouse Mus musculus Q9Z2A0 559 63740 T183 K I G S F D E T C T R F Y T A
Rat Rattus norvegicus O55173 559 63591 T183 K I G S F D E T C T R F Y T A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518589 320 36424
Chicken Gallus gallus Q6U1I9 432 48872 V113 G K G S F G K V L L A R H K A
Frog Xenopus laevis Q6GPN6 434 49096 V115 G K G S F G K V L L A R H Q A
Zebra Danio Brachydanio rerio Q7ZTW4 433 48964 V114 G K G S F G K V L L A R H R S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W0V1 836 94060 A345 R V G S F D V A C T R H Y A A
Honey Bee Apis mellifera XP_394208 537 61368 D180 K P E N I L L D E K M H V L I
Nematode Worm Caenorhab. elegans Q9Y1J3 636 71898 L172 H F G S F D M L T S K F F A S
Sea Urchin Strong. purpuratus XP_786576 539 61612 S182 K L G S F D E S S S R F Y T S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12236 1081 121642 T278 K Y G S L D E T C A R Y Y A A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 93.3 N.A. 94.8 95.3 N.A. 52.1 28.6 28 27.5 N.A. 32.5 54.1 32.5 58
Protein Similarity: 100 N.A. N.A. 95 N.A. 96.2 96.4 N.A. 54.6 44 43.8 43.3 N.A. 44.1 66.1 52.2 70.3
P-Site Identity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 0 26.6 26.6 20 N.A. 60 6.6 33.3 66.6
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 0 40 40 40 N.A. 73.3 13.3 60 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 35.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 66.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 8 0 8 24 0 0 24 62 % A
% Cys: 0 0 0 0 0 0 0 0 47 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 62 0 8 0 0 0 0 0 0 0 % D
% Glu: 0 0 8 0 0 0 47 0 8 0 0 0 0 0 0 % E
% Phe: 0 8 0 0 77 0 0 0 0 0 0 47 8 0 0 % F
% Gly: 24 0 85 0 0 24 0 0 0 0 0 0 0 0 0 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 16 24 0 0 % H
% Ile: 0 31 0 0 8 0 0 0 0 0 0 0 0 0 8 % I
% Lys: 54 24 0 0 0 0 24 0 0 8 8 0 0 8 0 % K
% Leu: 0 8 0 0 8 8 8 8 24 24 0 0 0 8 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % Q
% Arg: 8 0 0 0 0 0 0 0 0 0 54 24 0 8 0 % R
% Ser: 0 0 0 85 0 0 0 8 8 16 0 0 0 0 24 % S
% Thr: 0 0 0 0 0 0 0 39 8 39 0 0 0 39 0 % T
% Val: 0 8 0 0 0 0 8 24 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 0 8 54 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _