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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDPK1 All Species: 17.88
Human Site: T255 Identified Species: 32.78
UniProt: O15530 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15530 NP_002604.1 556 63152 T255 Y V S P E L L T E K S A C K S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537000 560 63701 T259 Y V S P E L L T E K S A C K S
Cat Felis silvestris
Mouse Mus musculus Q9Z2A0 559 63740 T258 Y V S P E L L T E K S A C K S
Rat Rattus norvegicus O55173 559 63591 T258 Y V S P E L L T E K S A C K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518589 320 36424 L64 D E K L Y F G L S Y A K N G E
Chicken Gallus gallus Q6U1I9 432 48872 V176 T A D K L Y F V L D Y I N G G
Frog Xenopus laevis Q6GPN6 434 49096 I178 T T S R L Y F I L D Y I N G G
Zebra Danio Brachydanio rerio Q7ZTW4 433 48964 V177 T T D K L Y F V L D Y I N G G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W0V1 836 94060 Q483 Y V S P E V L Q N G P I T P A
Honey Bee Apis mellifera XP_394208 537 61368 L249 Q Y V S P E L L T D K T S R A
Nematode Worm Caenorhab. elegans Q9Y1J3 636 71898 A283 Y V S P E M L A D G D V G P Q
Sea Urchin Strong. purpuratus XP_786576 539 61612 T260 Y V S P E L L T E K S A T K S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12236 1081 121642 N362 Y V S P E L L N D S F T D Y R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 93.3 N.A. 94.8 95.3 N.A. 52.1 28.6 28 27.5 N.A. 32.5 54.1 32.5 58
Protein Similarity: 100 N.A. N.A. 95 N.A. 96.2 96.4 N.A. 54.6 44 43.8 43.3 N.A. 44.1 66.1 52.2 70.3
P-Site Identity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 0 0 6.6 0 N.A. 40 6.6 40 93.3
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 6.6 0 6.6 0 N.A. 53.3 20 53.3 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 35.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 8 0 0 8 39 0 0 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 31 0 0 % C
% Asp: 8 0 16 0 0 0 0 0 16 31 8 0 8 0 0 % D
% Glu: 0 8 0 0 62 8 0 0 39 0 0 0 0 0 8 % E
% Phe: 0 0 0 0 0 8 24 0 0 0 8 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 8 0 0 16 0 0 8 31 24 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 8 0 0 0 31 0 0 0 % I
% Lys: 0 0 8 16 0 0 0 0 0 39 8 8 0 39 0 % K
% Leu: 0 0 0 8 24 47 70 16 24 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 8 0 0 0 31 0 0 % N
% Pro: 0 0 0 62 8 0 0 0 0 0 8 0 0 16 0 % P
% Gln: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % Q
% Arg: 0 0 0 8 0 0 0 0 0 0 0 0 0 8 8 % R
% Ser: 0 0 70 8 0 0 0 0 8 8 39 0 8 0 39 % S
% Thr: 24 16 0 0 0 0 0 39 8 0 0 16 16 0 0 % T
% Val: 0 62 8 0 0 8 0 16 0 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 62 8 0 0 8 24 0 0 0 8 24 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _