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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDPK1 All Species: 13.64
Human Site: T33 Identified Species: 25
UniProt: O15530 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15530 NP_002604.1 556 63152 T33 P S M V R T Q T E S S T P P G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537000 560 63701 T35 P S M V R T Q T E S G T A P G
Cat Felis silvestris
Mouse Mus musculus Q9Z2A0 559 63740 T33 P S M V R S Q T E P G S S P G
Rat Rattus norvegicus O55173 559 63591 T33 P S M V R S Q T E P S S S P G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518589 320 36424
Chicken Gallus gallus Q6U1I9 432 48872
Frog Xenopus laevis Q6GPN6 434 49096
Zebra Danio Brachydanio rerio Q7ZTW4 433 48964
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W0V1 836 94060 A74 F N I A T T T A T S A T E A T
Honey Bee Apis mellifera XP_394208 537 61368 K44 P T H K R T P K D F I F G K A
Nematode Worm Caenorhab. elegans Q9Y1J3 636 71898 L33 A A P T T L N L T P T A S E S
Sea Urchin Strong. purpuratus XP_786576 539 61612 S34 E A M S K H K S T D S Q P I S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12236 1081 121642 L73 K P M I Q K A L T N T D N F I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 93.3 N.A. 94.8 95.3 N.A. 52.1 28.6 28 27.5 N.A. 32.5 54.1 32.5 58
Protein Similarity: 100 N.A. N.A. 95 N.A. 96.2 96.4 N.A. 54.6 44 43.8 43.3 N.A. 44.1 66.1 52.2 70.3
P-Site Identity: 100 N.A. N.A. 86.6 N.A. 66.6 73.3 N.A. 0 0 0 0 N.A. 20 20 0 20
P-Site Similarity: 100 N.A. N.A. 86.6 N.A. 80 86.6 N.A. 0 0 0 0 N.A. 40 33.3 13.3 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 35.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 16 0 8 0 0 8 8 0 0 8 8 8 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 8 8 0 8 0 0 0 % D
% Glu: 8 0 0 0 0 0 0 0 31 0 0 0 8 8 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 8 0 8 0 8 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 16 0 8 0 31 % G
% His: 0 0 8 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 8 0 0 0 0 0 0 8 0 0 8 8 % I
% Lys: 8 0 0 8 8 8 8 8 0 0 0 0 0 8 0 % K
% Leu: 0 0 0 0 0 8 0 16 0 0 0 0 0 0 0 % L
% Met: 0 0 47 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 8 0 0 8 0 0 8 0 0 % N
% Pro: 39 8 8 0 0 0 8 0 0 24 0 0 16 31 0 % P
% Gln: 0 0 0 0 8 0 31 0 0 0 0 8 0 0 0 % Q
% Arg: 0 0 0 0 39 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 31 0 8 0 16 0 8 0 24 24 16 24 0 16 % S
% Thr: 0 8 0 8 16 31 8 31 31 0 16 24 0 0 8 % T
% Val: 0 0 0 31 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _