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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDPK1 All Species: 24.55
Human Site: T479 Identified Species: 45
UniProt: O15530 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15530 NP_002604.1 556 63152 T479 R R R Q L L L T E G P H L Y Y
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537000 560 63701 T483 R R R Q L L L T E G P H L Y Y
Cat Felis silvestris
Mouse Mus musculus Q9Z2A0 559 63740 T482 R R R Q L L L T E G P H L Y Y
Rat Rattus norvegicus O55173 559 63591 T482 R R R Q L L L T E G P H L Y Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518589 320 36424 F247 P L K A H P F F E S C T W E D
Chicken Gallus gallus Q6U1I9 432 48872 I359 N H I F F S P I N W D D L I N
Frog Xenopus laevis Q6GPN6 434 49096 I361 N H I F F S P I N W D D L I N
Zebra Danio Brachydanio rerio Q7ZTW4 433 48964 I360 N H M F F S P I N W D D L N A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W0V1 836 94060 T696 R K R M L L L T T G P R L I Y
Honey Bee Apis mellifera XP_394208 537 61368 T462 R R R M L L L T T G P H L Y Y
Nematode Worm Caenorhab. elegans Q9Y1J3 636 71898 T502 R R R M F L L T E G P H L L Y
Sea Urchin Strong. purpuratus XP_786576 539 61612 F458 V D K R K G L F A R R R M L L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12236 1081 121642 N966 E K E L L Q R N Q K V I E R R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 93.3 N.A. 94.8 95.3 N.A. 52.1 28.6 28 27.5 N.A. 32.5 54.1 32.5 58
Protein Similarity: 100 N.A. N.A. 95 N.A. 96.2 96.4 N.A. 54.6 44 43.8 43.3 N.A. 44.1 66.1 52.2 70.3
P-Site Identity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 6.6 6.6 6.6 6.6 N.A. 66.6 86.6 80 6.6
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 13.3 6.6 6.6 6.6 N.A. 73.3 86.6 80 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 35.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 0 8 0 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 0 0 0 24 24 0 0 8 % D
% Glu: 8 0 8 0 0 0 0 0 47 0 0 0 8 8 0 % E
% Phe: 0 0 0 24 31 0 8 16 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 8 0 0 0 54 0 0 0 0 0 % G
% His: 0 24 0 0 8 0 0 0 0 0 0 47 0 0 0 % H
% Ile: 0 0 16 0 0 0 0 24 0 0 0 8 0 24 0 % I
% Lys: 0 16 16 0 8 0 0 0 0 8 0 0 0 0 0 % K
% Leu: 0 8 0 8 54 54 62 0 0 0 0 0 77 16 8 % L
% Met: 0 0 8 24 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 24 0 0 0 0 0 0 8 24 0 0 0 0 8 16 % N
% Pro: 8 0 0 0 0 8 24 0 0 0 54 0 0 0 0 % P
% Gln: 0 0 0 31 0 8 0 0 8 0 0 0 0 0 0 % Q
% Arg: 54 47 54 8 0 0 8 0 0 8 8 16 0 8 8 % R
% Ser: 0 0 0 0 0 24 0 0 0 8 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 54 16 0 0 8 0 0 0 % T
% Val: 8 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 24 0 0 8 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 39 54 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _